Trental 400mg Tablet 30’S

About Trental 400mg Tablet 15’s

Trental 400mg Tablet 15’s belongs to a class of medicines called Hemorrheologic agent (affects blood viscosity), primarily used to treat pain in the legs due to insufficient blood flow (intermittent claudication). It also reduces cramping, numbness, or weakness in the legs on walking in such patients. Intermittent claudication is a peripheral vascular disease in which you have cramp-like pain in your legs when you walk and is caused by an insufficient blood supply in your legs.

Trental 400mg Tablet 15’s works by decreasing the viscosity (thickness) of blood, allowing it to pass more easily through the blood vessels especially in the small blood vessels of the hands and feet. It can also increase the distance you can walk without pain since it improves your legs’ blood circulation. It is recommended in patients whose pain has not improved even after lifestyle changes like quitting smoking and doing regular exercise.

Trental 400mg Tablet 15’s should be taken regularly in dose and duration as advised by the doctor. Your doctor will advise you on the exact dosage and how often you have to take Trental 400mg Tablet 15’s based on your medical condition. You may experience nausea, vomiting, diarrhea, headache, lightheadedness, sleep problems, intrahepatic cholestasis (removal of bile from the liver is blocked) abdomen pain constipation, urine discoloration in some cases. Most of these side effects of Trental 400mg Tablet 15’s do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Trental 400mg Tablet 15’s should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side-effects. Inform your doctor before starting Trental 400mg Tablet 15’s if you have any kidney or liver disease or plan to become pregnant or are breastfeeding. Also, lifestyle changes should be continued with Trental 400mg Tablet 15’s for best results. Do not take Trental 400mg Tablet 15’s if you ever had bleeding in your brain or the retina of your eyes heart failure, chest pain, heart disease, and blood pressure.

Uses of Trental 400mg Tablet 15’s

Intermittent claudication

Medicinal Benefits

Trental 400mg Tablet 15’s contains ‘Pentoxyfilline’ which is a peripheral vasodilator, works by decreasing the viscosity (thickness) of blood, allowing it to pass more easily through the blood vessels especially in the small blood vessels of the hands and feet. It can also increase the distance you can walk without pain since it improves your legs’ blood circulation. It is recommended in patients whose pain has not improved even after lifestyle changes like quitting smoking and doing regular exercise.

Directions for Use

Take Trental 400mg Tablet 15’s as advised by your doctor. Take with or without food. Swallow it as a whole, do not chew or crush it. Keep this medicine out of sight and reach of children.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trental 400mg Tablet 15’s

• Nausea
• Vomiting
• Diarrhea
• Headache
• Lightheadedness
• Sleep problems
• Intrahepatic cholestasis (removal of bile from the liver is blocked)
• Abdomen pain
• Constipation
• Urine discoloration

In-Depth Precautions and Warning

Drug Warnings

Do not take Trental 400mg Tablet 15’s if you are allergic to Trental 400mg Tablet 15’s or any other contents of it or any other medications. Inform your doctor if you are pregnant or breastfeeding. Before taking Trental 400mg Tablet 15’s, please tell your doctor if you are using any blood thinners as if they give together can increase the risk of severe bleeding. Trental 400mg Tablet 15’s is not intended for prolonged use unless prescribed by a physician. Inform your doctor if have had any type of bleeding in your brain or the retina of your eyes, low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease. Tell your doctor that you are using Trental 400mg Tablet 15’s before undergoing any dental or other surgery. Your doctor might stop this medicine before the surgery. Trental 400mg Tablet 15’s should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side-effects. Also, lifestyle changes should be continued with Trental 400mg Tablet 15’s for best results and a speedy recovery.

Drug Interactions

Drug-Drug Interaction: Trental 400mg Tablet 15’s may interact with blood thinners (warfarin, clopidogrel, aspirin), antibiotics (ciprofloxacin), pain relievers (ketorolac, diclofenac, indomethacin), antihypertensive (metoprolol, atenolol, propranolol, prazosin), antidiabetics ( metformin, alogliptin, linagliptin, saxagliptin, sitagliptin, canagliflozin), a drug used to treat lung diseases (theophylline), diuretics (furosemide, chlorothiazide, indapamide, metolazone),

Drug-Food Interaction: No interaction found/established.

Drug-Disease Interaction: Trental 400mg Tablet 15’s should be taken with caution in people who have bleeding problems, have had a heart attack, liver or kidney disease, pregnant women, or planning to get pregnant and breastfeeding women.

Safety Advice

• ALCOHOL
• Avoid consumption of alcohol with Trental 400mg Tablet 15’s as it may increase adverse effects such as dizziness, fainting, light-headedness or headache.
• PREGNANCY
• Trental 400mg Tablet 15’s is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.
• BREAST FEEDINGCONSULT YOUR DOCTOR
• Trental 400mg Tablet 15’s is not recommended for breastfeeding mothers as it may harm the baby.
• DRIVING
• Drive with caution, Trental 400mg Tablet 15’s may cause blurry vision, and dizziness or weariness may occur.
• LIVER
• Trental 400mg Tablet 15’s to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
• KIDNEY
• Trental 400mg Tablet 15’s to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

Habit Forming

No

Diet & Lifestyle Advise

• Keep your weight under control with body mass index (BMI) 19.5-24.9.
• Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
• Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
• Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
• If you are taking alcohol, then only one serving for women and two servings is advisable.
• Quitting smoking is the best strategy to lower the risk of heart disease.
• Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
• Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
• Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Special Advise

Your doctor may get regular blood tests done to monitor liver function while taking Trental 400mg Tablet 15’s as it might cause liver injury.

Patients Concern

Disease/Condition Glossary

Intermittent claudication: It is a peripheral vascular disease in which you have cramp-like pain in your legs when you walk and is caused by an insufficient blood supply in your legs.