About LEUPROSTA Depot 11.25mg Injection
LEUPROSTA Depot 11.25mg Injection belongs to the class of synthetic hormones used in the treatment of prostate cancer in men, endometriosis, and hormone-responsive breast cancer in women. Also, LEUPROSTA Depot 11.25mg Injection is used to treat premature puberty in children. Prostate cancer is cancer of the prostate gland (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems.
LEUPROSTA Depot 11.25mg Injection contains Leuprorelin, a synthetic hormone that works similarly to the natural hormone, gonadotropin-releasing hormone (GnRH), by acting on the pituitary gland and decreasing the levels of testosterone in men and estrogen in women. Thereby, LEUPROSTA Depot 11.25mg Injection is used in the treatment of prostate cancer by inhibiting the growth of the tumor or causing it to shrink.
Use LEUPROSTA Depot 11.25mg Injection as prescribed by your doctor. You are advised to take LEUPROSTA Depot 11.25mg Injection for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience pain, redness, swelling, or skin hardening at the injection site, muscle weakness, bone pain, inability to have an erection, breast tenderness, headache, vaginal dryness, changes in breast size, acne, or mood swings. Most of these side effects of LEUPROSTA Depot 11.25mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to LEUPROSTA Depot 11.25mg Injection or any other medicines, please tell your doctor. LEUPROSTA Depot 11.25mg Injection is contraindicated in pregnant and breastfeeding women. It is advised to use effective contraceptive measures to avoid pregnancy while taking LEUPROSTA Depot 11.25mg Injection as it may cause birth defects. LEUPROSTA Depot 11.25mg Injection should be used with caution in children. You are recommended to avoid or limit consumption of alcohol with LEUPROSTA Depot 11.25mg Injection as it may increase the risk of bone density loss. Drive only if you are alert as LEUPROSTA Depot 11.25mg Injection may cause dizziness, drowsiness, or vision disturbances.
Uses Of LEUPROSTA Depot 11.25mg Injection
- Prostate cancer, Breast cancer, Endometriosis, Premature puberty
Medicinal Benefits
LEUPROSTA Depot 11.25mg Injection contains Leuprorelin which works similarly to the natural hormone, gonadotropin-releasing hormone (GnRH), by acting on the pituitary gland and decreasing the levels of testosterone in men and oestrogen in women. Thereby, LEUPROSTA Depot 11.25mg Injection is used in the treatment of prostate cancer by inhibiting the growth of the tumour or causing it to shrink. Also, LEUPROSTA Depot 11.25mg Injection is used to treat hormone-responsive breast cancer in pre and postmenopausal women. By reducing testosterone and oestrogen levels, LEUPROSTA Depot 11.25mg Injection delays the onset of puberty in children.
Directions For Use
LEUPROSTA Depot 11.25mg Injection will be administered by a healthcare professional; do not self-administer.
Storage
- Store in a cool and dry place away from sunlight
Side Effects Of LEUPROSTA Depot 11.25mg Injection
In men:
- Muscle weakness
- Bone pain
- Inability to have an erection
- Tiredness
- Decreased interest in sex
In women:
- Breast tenderness
- Difficulty in sleeping
- Headache
- Vaginal dryness
- Changes in breast size
In children:
- Acne
- Mood swings
- Vaginal bleeding
- Pain, redness, swelling or skin hardening at the injection site
Precautions And Warning
If you are allergic to LEUPROSTA Depot 11.25mg Injection or any other medicines, please tell your doctor. LEUPROSTA Depot 11.25mg Injection is contraindicated in pregnant and breastfeeding women. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking LEUPROSTA Depot 11.25mg Injection as it may cause birth defects. LEUPROSTA Depot 11.25mg Injection should be used with caution in children. You are advised to quit smoking as it may increase the risk of prostate cancer. You are recommended to avoid or limit consumption of alcohol with LEUPROSTA Depot 11.25mg Injection as it may increase the risk of bone density loss. Drive only if you are alert as LEUPROSTA Depot 11.25mg Injection may cause dizziness, drowsiness or vision disturbances.
Interactions
Drug Interaction: LEUPROSTA Depot 11.25mg Injection may interact with antibiotics (moxifloxacin), heart-related medicines (procainamide, quinidine, sotalol, amiodarone), narcotic analgesics (methadone), antipsychotics (clozapine).
Food Interaction: No interactions found.
Disease Interaction: If you have abnormal vaginal bleeding, diabetes, osteoporosis (thinning of bones), depression, blood vessel disorder, seizures (fits), mental illness, spinal cord injury, brain tumor or heart disease, inform your doctor before taking LEUPROSTA Depot 11.25mg Injection.
Drug-Drug Interactions
- Moxifloxacin
- Procainamide
- Quinidine
- Sotalol
- Amiodarone
- Methadone
- Clozapine
Safety Advice
Alcohol
Avoid or limit alcohol consumption with LEUPROSTA Depot 11.25mg Injection as it may increase the risk of bone density loss.
Pregnancy
LEUPROSTA Depot 11.25mg Injection is not recommended for pregnant women as it may cause birth defects. Please consult a doctor if you are pregnant or planning for pregnancy.
Breast Feeding
LEUPROSTA Depot 11.25mg Injection is contraindicated in breastfeeding women. Please consult a doctor if you are breastfeeding.
Driving
LEUPROSTA Depot 11.25mg Injection may cause dizziness, drowsiness or disturbance in the vision. Therefore, avoid driving if you experience any of these symptoms after taking LEUPROSTA Depot 11.25mg Injection.
Liver
Take LEUPROSTA Depot 11.25mg Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
Take LEUPROSTA Depot 11.25mg Injection with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
LEUPROSTA Depot 11.25mg Injection should be used for children under the supervision of a paediatric endocrinologist.
Diet & Lifestyle Advise
- Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli, and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
- Avoid grilled meat, red meat, and saturated fat found in animal products, milk, and dairy products as they may increase the risk of prostate cancer.
- Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
- Quit smoking to reduce the risk of prostate cancer.
- Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
Special Advise
LEUPROSTA Depot 11.25mg Injection may cause changes in blood cholesterol levels or affect values in liver functioning tests. Therefore, inform your doctor that you are taking LEUPROSTA Depot 11.25mg Injection before undergoing any tests.
