About Amphomul 50mg Injection
AMPHOMUL 50mg Injection belongs to a class of medication called ‘antifungal’ used to treat severe fungal infections like leishmaniasis. A fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them.
AMPHOMUL 50mg Injection contains Amphotericin B, which kills fungi by destroying the fungal outer cell membrane. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.
AMPHOMUL 50mg Injection is given by a doctor or nurse. In some cases, you may experience fever, chills, irregular heartbeat, high or low blood pressure, breathing problems, nausea, vomiting, headache, shaking, muscle cramps or pain. Most of these side effects of AMPHOMUL 50mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to AMPHOMUL 50mg Injection or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using AMPHOMUL 50mg Injection. AMPHOMUL 50mg Injection is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking AMPHOMUL 50mg Injection as it may affect your ability to drive. If you experience severe adverse effects such as chest pain or difficulty in breathing, or encephalopathy (a brain disease which may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help.
Uses Of AMPHOMUL 50mg Injection
- Severe fungal infections
Medicinal Benefits
AMPHOMUL 50mg Injection contains Amphotericin B, an antifungal used to treat severe fungal infections. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. AMPHOMUL 50mg Injection damages fungal cell membranes and kills fungi. AMPHOMUL 50mg Injection is used to treat infections such as blood infection with candida, cryptococcus, fusarium, zygomycetes, aspergillus, coccidiodes or blastomycetes, or cryptococcal meningitis (inflammation of the brain).
Directions For Use
AMPHOMUL 50mg Injection will be administered by a healthcare professional; do not self-administer.
Storage
- Store in a cool and dry place away from sunlight
Side Effects Of AMPHOMUL 50mg Injection
- Fever
- Chills
- Irregular heartbeat
- High or low blood pressure
- Breathing problems
- Nausea
- Vomiting
- Headache
- Shaking
- Muscle cramps or pain
Precautions And Warning
If you are allergic to Amphotericin B or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using AMPHOMUL 50mg Injection. AMPHOMUL 50mg Injection is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking AMPHOMUL 50mg Injection as it may affect your ability to drive. If you experience severe adverse effects such as chest pain, difficulty breathing, or encephalopathy (a brain disease that may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help. If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking AMPHOMUL 50mg Injection.
Interactions
Drug Interaction: AMPHOMUL 50mg Injection may interact with an anti-HIV drug (zidovudine), immunosuppressant (ciclosporin), antifungal (flucytosine), water pills (furosemide), anticancer drug (methotrexate).
Food Interaction: No interactions found.
Disease Interaction: If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking AMPHOMUL 50mg Injection.
Drug Interactions
- Zidovudine
- Ciclosporin
- Flucytosine
- Furosemide
- Methotrexate
Safety Advice
Alcohol
The interaction of AMPHOMUL 50mg Injection with alcohol is unknown. Please consult your doctor if you have any concerns regarding this.
Pregnancy
AMPHOMUL 50mg Injection is a Category B pregnancy drug and is given to a pregnant woman if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning pregnancy.
Breast Feeding
It is unknown whether AMPHOMUL 50mg Injection is excreted in human milk. If you are breastfeeding, inform your doctor before receiving this injection.
Driving
Avoid driving after taking AMPHOMUL 50mg Injection as it may affect your ability to drive or operate machinery.
Liver
Inform your doctor if you have a history of liver diseases/conditions before receiving AMPHOMUL 50mg Injection.
Kidney
Inform your doctor if you have a history of kidney diseases/conditions before receiving AMPHOMUL 50mg Injection.
Children
AMPHOMUL 50mg Injection is not recommended for children below one month as the safety and effectiveness were not established.
Diet & Lifestyle Advise
- Wash your hands regularly and keep your hands clean to prevent the spread of germs.
- Avoid dusty activities and digging in the soil.
- Wear shoes, a long-sleeved t-shirt and long pants while doing outdoor activities such as yard work, gardening or visiting wooded areas to protect from fungus commonly present in the environment.
- Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.
Special Advise
- Regular blood tests are recommended while taking AMPHOMUL 50mg Injection to monitor blood, liver or kidney functioning and potassium levels.
