INTRODUCTION
COGNIDEP 5 contains Donepezil which belongs to a group of medicines called acetyl cholinesterase inhibitors. It is used to treat the symptoms of dementia in people diagnosed as having mild and moderately severe Alzheimer’s disease. Alzheimer’s disease is a progressive disorder that causes brain cells to degenerate and die. Dementia is continuous decline in thinking, behavioral and social skills that disrupts a person’s ability to function independently. The symptoms include increasing memory loss, confusion and behavioral changes. As a result, patients with Alzheimer’s disease find it more difficult to carry out their normal daily activities.
COGNIDEP 5 works by stopping acetylcholine from being broken down in your brain. Acetylcholine is an important substance that allows better communication between nerve cells. Always take this medicine as prescribed by your doctor. Before using this medicine, inform your doctor if you have heart problems, stomach ulcers, epilepsy, or asthma, pregnant or breastfeeding. It is not recommended for use in children and adolescents below 18 years of age. The common side effects are diarrhoea, headache, tiredness and hallucinations.
USES OF COGNIDEP 5
- Alzheimer’s disease (dementia)
HOW COGNIDEP 5 WORKS
COGNIDEP 5 works by stopping acetylcholine from being broken down in your brain. Acetylcholine is an important substance that allows better communication between nerve cells. Always take this medicine as prescribed by your doctor.
DIRECTIONS FOR USE
Take this COGNIDEP 5 according to the dose and frequency as advised by your doctor. Swallow it as a whole. Do not chew, crush or break the medicine. It may be taken with or without food.
SIDE EFFECTS OF COGNIDEP 5
SERIOUS
- Stomach pain and discomfort (indigestion)
- Bleeding in the stomach or intestines
- Seizures (fits) or convulsions
- Liver damage
- Fever with muscle stiffness, sweating or a lowered level of consciousness
- Rhabdomyolysis
COMMON
- Diarrhoea, feeling sick, vomiting
- Headache
- Muscle cramp, tiredness
- Difficulty in sleeping
- Common cold
- Loss of appetite
- Unusual dreams including nightmares
- Aggressive behaviour
- Fainting, dizziness
- Rash, itching
- Passing urine uncontrollably
RARE
- Stiffness, shaking or uncontrollable movement especially of the face and tongue but also of the limbs
- Disturbance in heart rhythm
HOW TO MANAGE SIDE EFFECTS
Diarrhoea:
Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.
Drowsiness or dizziness:
Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.
Vomiting:
Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.
Constipation:
Eat fruits, vegetables whole grains and high fiber rich foods.
Feeling sick (nausea) or indigestion:
Stick to simple normal meals and do not eat rich or spicy foods.
WARNING & PRECAUTIONS
PREGNANCY
COGNIDEP 5 is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
COGNIDEP 5 is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate machinery while taking this medicine, since it may cause tiredness, dizziness and muscle cramp.
ALCOHOL
Consumption of alcohol is not recommended during treatment with COGNIDEP 5.
KIDNEY
COGNIDEP 5 should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
LIVER
COGNIDEP 5 should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.
ALLERGY
Do not take if you are allergic (hypersensitive) to Donepezil or any ingredients of this medicine.
HEART DISEASE
COGNIDEP 5 should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.
OTHERS
Tell your doctor if you had or have a condition such as:
- Stomach or duodenal ulcers
- Seizures (fits) or convulsions
- Asthma or other long term lung disease
INTERACTIONS
Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:
- Galantamine
- Ibuprofen, diclofenac sodium
- Tolterodine
- Erythromycin, rifampicin
- Ketoconazole
- Fluoxetine
- Phenytoin, carbamazepine
- Quinidine, beta-blockers (propanolol and atenolol)
- Diazepam, succinylcholine
- General anaesthetics
SYNOPSIS
| Drug | : | Donepezil |
| Pharmacological Category | : | Acetyl cholinesterase Inhibitor (Central) |
| Therapeutic Indication | : | Alzheimer disease, Dementia |
| Dosage Forms | : | Tablet, Syrup |
MORE INFORMATION
Do not store above 30ºC and keep out of reach of children.
FAQs ABOUT COGNIDEP 5
For how long does COGNIDEP 5 stay in your system?
It gets removed from the body very slowly. It takes about two weeks or more for this medicine to be completely removed from the system.
Does COGNIDEP 5 cause depression?
No, it does not cause depression. If you are experiencing symptoms, then it could be due to existing Alzheimer’s disease.
Can COGNIDEP 5 cause insomnia?
Yes, it may cause insomnia (sleeplessness). Dizziness and fainting can also be seen as common side effects.
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