Xospata 40mg, Gilteritinib Tablets

Xospata 40mg is a targeted oral cancer medication containing Gilteritinib, used to treat relapsed or refractory acute myeloid leukemia (AML) in adults with a FLT3 gene mutation. It works by blocking the FLT3 protein, helping to stop the growth of leukemia cells. Xospata offers a personalized treatment option and is taken once daily under medical supervision.

What is the generic for gilteritinib?

• Gilteritinib” is both the generic name and the international nonproprietary name (INN) for the drug, while brand names include Xospata (by Astellas) and Xospata (by Lucius Pharmaceuticals in some markets).
• If you’re asking about generics in terms of non-branded alternatives, Xospata itself is a generic version of Gilteritinib, typically available in markets where branded Xospata is not the primary option.
• The generic name for gilteritinib is Xospata, which is another brand name under which this medication is marketed.

What is Xospata 40mg (Gilteritinib)?

• Xospata 40mg is a targeted cancer therapy that contains Gilteritinib, a FLT3 inhibitor. It is mostly used to treat acute myeloid leukemia (AML) that has a FLT3 gene.
• Xospata (Gilteritinib) is used to treat adult patients with relapsed or refractory acute myeloid leukemia (AML) that carries a mutation in the FLT3 gene.

How Does Xospata Work?

Gilteritinib targets and inhibits FLT3 (FMS-like tyrosine kinase 3), a gene mutation often found in AML that promotes the growth of abnormal white blood cells.

By blocking the FLT3 signaling pathway, Gilteritinib helps to stop the growth and survival of leukemic cells in the bone marrow.

How to Use Xospata 40mg?

Take Xospata 40mg by mouth once a day, at the same time each day, to maintain a consistent level of the medication in your body.

How to take it:

• Form: Xospata comes in a tablet form that you swallow whole, usually once a day.
• Timing: It’s important to take the medicine exactly as prescribed by your doctor, at the same time each day, with or without food.

How long can you take Gilteritinib?

You can take Gilteritinib as long as it remains effective and well-tolerated, or until the disease progresses or serious side effects occur. 

Missed Dose

• Don’t do it twice the next day.

Other Dosages of Gilteritinib

Xospata is typically available in 40mg strength, and the recommended dose is 120 mg once daily (i.e., 3 tablets of 40mg). Adjustments may be made based on individual tolerance or side effects

When treating AML, gilteritinib is usually taken orally once a day at a dose of 120 mg until the illness worsens or the toxicity becomes unbearable.

Side Effects of Xospata (Gilteritinib)

Common side effects include:

• Fatigue
• Elevated liver enzymes
• Diarrhea
• Nausea
• Cough
• Muscle pain
• Serious side effects:
• QT prolongation (irregular heart rhythm)
• Differentiation syndrome
• Liver toxicity
• If you have breathing difficulties, chest pain, or symptoms of liver disease, such as yellowing of the eyes or skin, get medical help right once.

Prescription Information:

Xospata 40mg (Gilteritinib) is a prescription-only medication. It must be prescribed and supervised by a qualified oncologist or hematologist experienced in treating AML.

Drug Interactions with Xospata: 

Gilteritinib may interact with drugs that affect CYP3A4 enzyme such as:

• Antifungals (e.g., ketoconazole)
• Anticonvulsants (e.g., phenytoin)
• Certain antibiotics (e.g., rifampin)
• Avoid using strong CYP3A4 inhibitors or inducers unless absolutely necessary, as they can alter Gilteritinib plasma levels.

FAQs:

• Can Xospata 40mg be used in combination with other chemotherapy drugs?

Yes, Xospata 40mg can be used in combination with other chemotherapy drugs for the treatment of AML.

• How is Xospata 40mg taken?

Xospata 40mg is taken orally, usually once daily with or without food.

• Can Xospata 40mg be prescribed by any doctor?

Xospata 40mg is a prescription medication and should be prescribed by a healthcare provider familiar with the treatment of AML.

Conclusion:

A precision oncology drug called Xospata 40mg (Gilteritinib) is used to treat relapsed or refractory AML that has FLT3 mutations. With proper medical supervision, it offers targeted action with a manageable side effect profile. Due to its potential risks and drug interactions, it must be taken exactly as prescribed by a healthcare professional.”

In summary, Xospata (gilteritinib) is a targeted oral medication for adults with relapsed or refractory AML who have a specific FLT3 mutation. Treatment duration is determined by your doctor based on your response and tolerance. It’s important to follow your doctor’s instructions carefully and be aware of potential side effects.