Ganaton total capsule contains enteric-coated pantoprazole and sustained-release itopride which is used in the treatment of gastroesophageal reflux disease (acid reflux) and peptic ulcer disease. Pantoprazole suppresses the gastric acid secretion by inhibiting the proton-pump in parietal cell membrane which helps in the relief of acid-related indigestion and heartburn. The enteric coating given to pantoprazole resists its dissolution under acidic conditions (e.g. stomach pH) and makes it soluble at the basic conditions of the intestinal tract. Itopride belongs to the class of drugs called gastroprokinetic agent which improves the motility of gastrointestinal tract and prevent from nausea and vomiting. Ganaton Total Capsule activates acetylcholine release and inhibits its degradation which in turn, promotes gastric motility and accelerates gastric emptying. Sustained release of itopride helps in achieving an optimum concentration of the drug over a period of time.
Ganaton Total Capsule should be taken once daily before meals. Ganaton Total Capsule should not be used in patients in whom an increase in gastrointestinal motility could be harmful, e.g. gastrointestinal hemorrhage, mechanical obstruction or perforation.
THERAPEUTIC USES OF GANATON TOTAL CAPSULE:
Ganaton Total Capsule is used in the treatment of gastroesophageal reflux disease (acid reflux) and peptic ulcer disease.
HOW GANATON TOTAL CAPSULE WORKS?
Pantoprazole exerts its stomach acid-suppressing effects by inhibiting the enzyme called (H , K )-ATPase at the secretory surface of gastric parietal cells. As a result, it provides relief of acid-related indigestion and heartburn, while itopride inhibits the enzyme called anticholinesterase and prevents the degradation of acetylcholine in the gut wall. As a result of this, the concentration of acetylcholine increases, which in turn, promotes gastric motility, increases the lower esophageal sphincter pressure, accelerates gastric emptying and improves gastro-duodenal coordination.
DIRECTIONS FOR USE:
Always take Ganaton total capsule exactly as your doctor has told you. It should be swallowed as whole with a drink of water. Do not crush or chew the medicine. It should be taken once daily 1 hour before meals.
SIDE EFFECTS OF GANATON TOTAL CAPSULE:
• Feeling sick (nausea) or being sick (vomiting)
• Bloating or flatulence
• Impaired sleeping
• Dizziness, fatigue or irritability
• Back pain or chest pain
• Benign polyps in stomach
• Skin rash or itching
• Fracture in the hip, wrist or spine.
• Lack of the sense of taste
• Blurred vision
• Muscle pains
• Weight changes
• High fever
• Swelling of the extremities (oedma)
• Breast enlargement in males
Swelling of the tongue and/or throat
Difficulty in swallowing/breathing
HOW TO MANAGE SIDE EFFECTS:
Feeling sick (nausea) or being sick (vomiting):
Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Bloating or wind;
Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. If the symptoms get worse, contact your doctor straight away.
Eat fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise regularly.
Drink lots of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines to treat diarrhea without speaking to a doctor.
Try to rest and relax. You can also eat and drink slowly or have smaller and frequent meals. Keep a heat pad or covered hot water bottle on your stomach may also help. If still pain persists, speak to your doctor.
WARNING AND PRECAUTIONS:
This medicine should be used with caution in pregnant women. Consult your doctor before taking.
It is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
Avoid drinking alcohol while taking this medicine.
If you think your medicine is affecting your driving, don?t stop taking your medication. Stop driving and talk to your doctor.
This medicine should be used with caution in patients suffering from severe liver problems. Talk to your doctor, pharmacist or nurse before taking this medicine.
This medicine should be used with caution in patients suffering from severe kidney problems. Talk to your doctor, pharmacist or nurse before taking this medicine.
This medicine should not be used in patients in whom an increase in gastrointestinal motility could be harmful, e.g. gastrointestinal hemorrhage, mechanical obstruction or perforation. This medicine should be used with caution in elderly patient, as risk of decreased hepatic and renal function can occur.
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:
Talk to your doctor, if you are taking,
Anticholinergic agents (e.g. atropine, belladonna alkaloids, clidinium, cyclopentolate, darifenacin or dicylomine)
Keep taking this medicine even if you feel well, as you will still be getting the benefits. Store this medication at room temperature and keep it out of the reach of children.
FAQ?s ABOUGANATON TOTAL CAPSULE:
Q: Can Ganaton total capsule be taken by pregnant women?
A: This medicine should be used with caution in pregnant women. Consult your doctor before taking.
Q: Can I stop taking Ganaton total capsule abruptly?
A: Do not stop taking this medicine without consulting your doctor. Stopping this medicine suddenly may result in another such problem.
Q: Can Ganaton total capsule be used in elderly patients?
A: This medicine should be used with caution in elderly patient, as risk of decreased hepatic and renal function can occur. Kindly consult with your doctor before taking.
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