Mext 15mg Tablet 10’S

$16

Methotrexate 15 mg

In stock

INTRODUCTION:

MEXT 15MG contains methotrexate which belong to a group of medicines called folate antagonist. It can be used to treat severe cases of psoriasis and rheumatoid arthritis. It can also be used to treat several kinds of cancer. Psoriasis is an autoimmune disorder that causes your skin cells to grow and multiply much quickly than normal cells. Methotrexate kills the rapidly multiplying cells in the skin. In rheumatoid arthritis, methotrexate reduce inflammation in joints by altering body’s defence mechanism in immune system. In cancer, methotrexate inhibits the enzymes responsible for nucleotide synthesis and prevents cell division.

Always take this medicine as directed by your physician. Swallow the medicine as a whole with a glass of water. Do not crush or chew the medicine. Your doctor will decide the dose and duration of the therapy depending upon your health condition. This medicine should be used with caution in children and in elderly patient. Consult your doctor before taking this medicine. The common side effects are nausea or vomiting, anorexia (eating disorder), a skin rash with reddening of the skin, hair loss.

USES OF MEXT 15MG:

Treat severe cases of psoriasis and rheumatoid arthritis if other treatments are not effective
Treat several kinds of cancer, including acute leukemias, non-Hodgkin?s lymphoma, soft tissue and bone sarcomas, solid tumors like breast, lung, head and neck, bladder, cervical, ovarian and testicular cancer

HOW MEXT 15MG WORKS:

Methotrexate inhibits the enzymes responsible for nucleotide synthesis including dihydrofolate reductase, thymidylate synthase, aminoimidazole caboxamide ribonucleotide transformylase (AICART) and amido phosphoribosyl transferase which prevents cell division and leads to anti-inflammatory actions.

Since cellular proliferation in malignant tissues (cancerous tissue) are greater than in most normal tissues, methotrexate may impair malignant growth without causing any irreversible damage to normal tissues. Methotrexate has immunosuppressive effects, and this might be a result of inhibition of lymphocyte multiplication. In psoriasis, it kills the rapidly multiplying skin cells.

DIRECTIONS FOR USE:

Always take MEXT 15MG as directed by your physician. Your doctor will decide the dose and duration of the therapy depending upon your age, weight and condition. Swallow the medicine as a whole with a glass of water. Do not crush or chew.

SIDE EFFECTS OF MEXT 15MG:

COMMON

• Nausea or vomiting
• Anorexia (eating disorder)
• A skin rash with reddening of the skin
• Hair loss
• A lump in your neck, groin or armpits with associated backache, weight loss or night sweats
• Nosebleed
• Vaginal ulcers

RARE

• Herpes zoster infection
• Depression, confusion, loss of interest in, or inability to have sex
• Tenderness and swelling of the lower extremities (clot in the veins)
• Difficulty in breathing
• Throat infection
• Swelling of the gums
• Abdominal pain, cramping, diarrhoea, dehydration, fever and weight loss
• Muscle pain, joint pain
• Weakening or softening of bones
• Menstrual disorders or impotence

HOW TO MANAGE SIDE EFFECTS:

Nausea or vomiting:

Try taking this medicine with, or just after, a meal. Stick to simple meals.

Diarrhea:

Drink lots of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

WARNINGS AND PRECAUTIONS:

PREGNANCY

MEXT 15MG should be used with caution in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

MEXT 15MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate any machinery while taking this medicine, as it may make you feel dizzy or drowsy.

ALCOHOL

Avoid consumption of alcohol while taking this medicine.

KIDNEY

MEXT 15MG should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.

LIVER

MEXT 15MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic to methotrexate.

LUNGS

MEXT 15MG should be taken with caution in patients with lung disease. Consult your doctor for advice.

OTHERS

Do not take this medicine, if you have:

Any serious blood disorders including severe anemia, leucopenia (decreased white cells count), thrombocytopenia (decreased platelet count) or any serious infection

INTERACTIONS:

Talk to your doctor, if you are taking,

Non-steroidal anti-inflammatory drugs (e.g. ibuprofen, indomethacin or aspirin)
Diuretics (used to increase water output) e.g. furosemide, hydrochlorothiazide
Medicines used to treat epilepsy (e.g. phenytoin, carbamazepine and valproate)
Medicines used to treat diabetes e.g. metformin
Medicines used to treat gout e.g. probenecid or sulfinpyrazone
Medicines used to treat stomach ulcers e.g. omeprazole or pantoprazole
Medicines used to suppress immune response e.g. leflunomide or ciclosporin
Other medicines against cancer (e.g. cisplatin)
Antibiotics (used to treat bacterial infections) including penicillin, sulphonamides, trimethoprim/sulfamethoxazole, neomycin, ciprofloxacin, doxycycline, tetracyclines, chloramphenicol
Olanzapine (used to treat schizophrenia)
Pyrimethamine (used to treat malaria)
Digoxin (used to treat heart failure)
Theophylline (used to treat asthma)
P-aminobenzoic acid (used to treat skin disorders)
Corticosteroids used for the treatment of arthritis, allergic reactions or skin diseases
Retinoids used for the treatment of skin disorders e.g. acitretin
Vitamin preparations containing folic acid or similar products

SYNOPSIS:

Drug : Methotrexate
Pharmacological Category : Antimetabolite, Antirheumatic, Immunosuppressant Agent
Therapeutic Indication : Psoriasis, Rheumatoid arthritis, Cancer
Dosage Forms : Tablet, Injection, Gel

MORE INFORMATION:

Store below 20-25°C and keep out of reach of children.

FAQ’s ABOUT MEXT 15MG:

Q: Will MEXT 15MG affects fertility?
A: Yes. This medicine may temporarily affect sperm and egg production and cause infertility.

Q: Can MEXT 15MG be used in pregnant women?
A: No. This medicine is strictly not recommended for use in pregnant women. Consult your doctor before taking.

CONTACT US

Email: contact@24x7pharma.com

Business Hours

We are operated 24*7 (But Limited to Email Support)
Email Support Timing (All times India Standard Time (IST)
Monday - Saturday : (08:00 AM - 10:00 PM)
Sunday : (08:00 AM - 06:00 PM)

Do you have questions about how we can help your company?
Send us an email and we’ll get in touch shortly.

Order confirmation

When you place your order we will immediately email you an order confirmation. Within 24 hours you should receive a second email to confirm your order is now in processing. If we are unable to fulfill your order or there is a payment problem we will email you.

Shipping confirmation

Once your order is in processing it will likely be shipped that day. A shipping confirmation will be emailed to you accompanied with a track and trace number if applicable. The email will outline typical shipping times and how to contact us if you have any questions.

We can ship to your home address or to your work if you prefer.

Registered airmail is the preferred shipping method as it is more secure and less likely to be stolen or lost. It does require a signature on delivery. If you are not available at the time of delivery a notice will be left to advise of the attempted delivery and how to contact the post office to arrange a redelivery or at which post office it is be stored for collection. They will hold them there for 4 weeks before they are returned to us.

PO Boxes and APO Addresses

We can deliver to PO Boxes and APO addresses as long as the delivery method. On your My Account page, simply set your Primary Shipping Address to your PO Box or APO address as required.

Customs

We are based off shore in India and your order is treated by your local Customs as imported goods. When your parcel passes through Customs there might be a delay while they process your order. We suggest that you always allow extra time and order ahead so you are not inconvenienced during this phase. The delay can be just a few days to 3 weeks in extreme cases before they contact you.

Delivery times

We promptly ship most orders within 24-48 hours of you placing it. The delivery times are entirely due to the postal or courier service. The table above shows the typical delivery times. Please be aware that if customs hold your order for pending import duties, they could hold your order for 3-21 days prior to contacting you. If your order hasn’t arrived within the standard delivery times above, please allow an additional 7 days for delivery PRIOR to contacting us to establish if your order is simply delayed with delivery; held at customs or indeed lost.