Nintena 100mg Capsule contains Nintedanib 100mg, a tyrosine kinase inhibitor used in adults for certain fibrosing lung diseases. Nintena 100mg is supplied as a soft gelatin capsule for oral use. It is a prescription medicine and should be taken only under the supervision of a qualified healthcare professional.
Nintedanib works by blocking several signalling pathways involved in abnormal tissue growth and fibrosis. This action can help slow the decline in lung function in eligible patients with certain progressive fibrosing lung diseases. The medicine does not remove existing lung scarring or cure pulmonary fibrosis.
For additional information about nintedanib medicines, you can also explore Idiopathic Pulmonary Fibrosis medicines available at 24x7Pharma.
What Is Nintena 100mg Capsule?
Nintena 100mg Capsule is an oral prescription medicine containing Nintedanib 100mg. Nintedanib belongs to the tyrosine kinase inhibitor class. Doctors use it to slow disease progression in certain fibrosing lung conditions.
Fibrosing lung diseases can cause progressive thickening and scarring of lung tissue. Over time, this process may reduce lung function. Nintedanib targets signalling pathways that contribute to fibrosis and abnormal tissue repair.
Nintena 100mg should not be used for unexplained breathing problems without a proper diagnosis. Your doctor will assess your condition, medical history and treatment requirements before prescribing this medicine.
Composition
| Product Information | Details |
|---|---|
| Brand Name | Nintena |
| Active Ingredient | Nintedanib |
| Strength | 100mg |
| Dosage Form | Soft Gelatin Capsule |
| Route | Oral |
| Drug Class | Tyrosine Kinase Inhibitor |
| Pack Size | 1 x 10 Capsules |
| Manufacturer / Marketer | Sun Pharmaceutical Industries Ltd. |
Uses
The exact indication depends on the patient’s diagnosis and the applicable prescribing information.
Idiopathic Pulmonary Fibrosis
Nintedanib is used to slow the progression of Idiopathic Pulmonary Fibrosis (IPF). IPF causes progressive scarring of lung tissue. This scarring can reduce the ability of the lungs to transfer oxygen and may lead to increasing breathlessness over time.
Progressive Fibrosing Interstitial Lung Disease
Nintedanib is also used for certain chronic fibrosing interstitial lung diseases that show a progressive phenotype. Treatment aims to reduce the rate of decline in lung function.
Systemic Sclerosis-Associated Interstitial Lung Disease
In applicable treatment settings, nintedanib may also be prescribed for systemic sclerosis-associated interstitial lung disease. The treatment decision should come from a specialist after reviewing the patient’s condition.
Selected Oncology Use
Indian medicine references also describe nintedanib use in specific non-small cell lung cancer treatment settings, usually as part of specialist-directed combination therapy. Because oncology treatment depends on the cancer type, previous treatment and local prescribing information, Nintena 100mg should not be used for cancer without an oncologist’s prescription.
Current U.S. prescribing information primarily identifies nintedanib capsules for idiopathic pulmonary fibrosis and chronic fibrosing interstitial lung diseases with a progressive phenotype. Always follow the prescribing information applicable to the patient’s country and indication.
How Does Nintena 100mg Capsule Work?
Nintena 100mg contains nintedanib. It works by inhibiting several receptor tyrosine kinases involved in signalling pathways that promote fibrosis and abnormal tissue growth.
These pathways include signalling associated with growth factors involved in the development of fibrotic tissue. By reducing this signalling, nintedanib can slow the progression of fibrosis in eligible patients.
The medicine does not reverse established lung scarring. Instead, its main role is to reduce the rate at which lung function declines in approved conditions.
For authoritative prescribing information, refer to DailyMed nintedanib information.
Nintena 100mg Capsule Benefits
When prescribed for an appropriate condition, Nintena 100mg may provide the following treatment benefits:
- Helps slow the progression of certain fibrosing lung diseases.
- May reduce the rate of decline in lung function.
- Targets signalling pathways involved in fibrosis.
- Supports long-term management of eligible patients with progressive fibrosing lung disease.
- Provides an oral treatment option for specialist-directed antifibrotic therapy.
The response varies between patients. Treatment benefits depend on the underlying disease, disease progression, treatment adherence and overall health.
Nintena 100mg Dosage
The appropriate dose of Nintedanib depends on the indication, tolerability, liver function and other clinical factors. Your doctor will decide the dose and duration of treatment.
Do not assume that the 100mg strength means that every patient should take 100mg twice daily. The current prescribing information lists 150mg twice daily as the recommended dose for several adult indications. A 100mg twice-daily dose may be used in patients with mild hepatic impairment or when the doctor reduces the dose because of adverse reactions.
Therefore, take Nintena 100mg exactly as prescribed. Do not increase, decrease or stop the dose on your own.
How to Take Nintena 100mg Capsule
- Take the capsule exactly as prescribed by your doctor.
- Take Nintena 100mg with food.
- Swallow the capsule whole with liquid.
- Do not chew the capsule.
- Do not open or crush the capsule.
- Take the medicine at the scheduled time recommended by your doctor.
Taking nintedanib with food can help improve tolerability. Follow the instructions provided with your prescription and product packaging.
Missed Dose of Nintena 100mg
If you miss a dose, take your next dose at the regular scheduled time. Do not take an extra capsule to make up for a missed dose.
If you frequently miss doses, discuss the problem with your doctor or pharmacist. They can help you maintain a consistent treatment schedule.
Nintena 100mg Capsule Side Effects
Nintedanib can cause side effects. Some effects are mild and may improve with appropriate medical management. However, persistent or severe symptoms require medical attention.
Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain or discomfort
- Reduced appetite
- Weight loss
- Headache
- Increased liver enzymes
- Fatigue
Diarrhea is one of the most frequently reported adverse effects of nintedanib. Drink adequate fluids if diarrhea occurs and contact your doctor if symptoms are severe, persistent or associated with dehydration.
Serious Side Effects
Seek prompt medical attention if you develop severe or persistent symptoms such as:
- Severe or persistent diarrhea
- Signs of significant liver problems
- Unusual bleeding or bruising
- Severe abdominal pain
- Chest pain or symptoms of an arterial thromboembolic event
- Symptoms of a serious allergic reaction
- Symptoms that suggest gastrointestinal perforation
Nintena 100mg Precautions and Warnings
Nintedanib requires medical supervision because it can affect the liver and gastrointestinal system. It can also increase the risk of bleeding in susceptible patients.
- Tell your doctor if you have liver disease.
- Inform your doctor about any history of bleeding problems.
- Tell your doctor about heart or vascular disease.
- Inform your doctor about planned surgery.
- Tell your doctor about all prescription and non-prescription medicines.
- Tell your doctor about vitamins and herbal supplements.
- Report severe diarrhea or vomiting promptly.
- Attend all recommended laboratory tests.
Nintena 100mg and Liver Function
Nintedanib can increase liver enzymes and may cause drug-induced liver injury. Doctors may check liver function before starting treatment and during therapy.
Patients with mild hepatic impairment may require a lower dose. Nintedanib is not recommended for patients with moderate or severe hepatic impairment according to current U.S. prescribing information.
Tell your doctor if you have previously experienced hepatitis, abnormal liver tests, liver disease or other liver-related problems.
Nintena 100mg and Kidney Problems
Tell your doctor if you have kidney disease or a history of kidney problems. Your healthcare professional will review your medical history and decide whether Nintedanib is appropriate for you.
Do not change the dose based on kidney function without medical advice.
Nintena 100mg During Pregnancy
Nintedanib may cause harm to an unborn baby. Women who can become pregnant should discuss pregnancy prevention with their healthcare professional before starting treatment.
Pregnancy testing may be required before treatment in women of reproductive potential. If pregnancy occurs while taking Nintena 100mg, contact your doctor immediately.
For detailed prescribing information, visit the official nintedanib prescribing information.
Nintena 100mg and Breastfeeding
The safety of breastfeeding during nintedanib treatment should be discussed with your doctor. Because the potential risk to a breastfed infant cannot be ignored, your healthcare professional will consider the benefits of treatment and the potential risks before giving advice.
Nintena 100mg Drug Interactions
Several medicines can change nintedanib exposure. This can affect treatment response or the risk of adverse effects.
Tell your doctor about every medicine and supplement you take. Important medicines to discuss include:
- Rifampicin
- Carbamazepine
- Phenytoin
- Medicines that affect bleeding risk
- Medicines that affect liver enzyme or transporter activity
- Other prescription medicines used for chronic diseases
Do not start a new medicine, supplement or herbal product without discussing it with your healthcare professional.
Nintena 100mg and Food
Nintena 100mg should be taken with food. Swallow the soft gelatin capsule whole with liquid.
If diarrhea, nausea or vomiting becomes difficult to manage, contact your healthcare provider. Your doctor may recommend supportive treatment or adjust your therapy when appropriate.
Nintena 100mg and Alcohol
There is no general instruction to use alcohol as part of Nintena treatment. However, excessive alcohol consumption may place additional stress on the liver.
Ask your doctor whether alcohol is appropriate for you, especially if you have liver disease or abnormal liver tests.
Nintena 100mg and Smoking
Smoking can worsen lung health and may affect treatment outcomes in people with chronic respiratory disease. If you smoke, speak with your healthcare professional about a suitable smoking cessation plan.
Nintena 100mg Monitoring
Regular monitoring can help your healthcare professional identify adverse effects early and assess your response to treatment.
- Liver function tests may be required.
- Pregnancy testing may be required before treatment in women of reproductive potential.
- Your doctor may monitor gastrointestinal symptoms.
- Blood pressure and cardiovascular symptoms may require attention.
- Weight and nutritional status may be reviewed when significant diarrhea or appetite loss occurs.
Nintena 100mg Overdose
Do not take more Nintena 100mg than prescribed. An overdose can increase the risk of adverse effects.
If you think you have taken more capsules than prescribed, contact a healthcare professional or seek urgent medical attention. Do not wait for symptoms to become severe.
Nintena 100mg Storage
Store Nintena 100mg according to the instructions printed on the product packaging. Current Indian medicine listings advise storage below 25°C.
- Keep the medicine in its original packaging.
- Protect it from excessive heat and moisture.
- Keep the capsules away from direct sunlight.
- Keep the medicine out of reach of children.
- Do not use the medicine after the expiry date.
Who Should Use Nintena 100mg?
Nintena 100mg is intended for adults who have been evaluated by a qualified healthcare professional and have a condition for which nintedanib treatment is appropriate.
This medicine should not be selected only because of symptoms such as cough or breathlessness. These symptoms can occur with many different conditions. A specialist diagnosis is important before starting antifibrotic therapy.
Buy Nintena 100mg Capsule Online
If Nintena 100mg Capsule has been prescribed for you, verify the product name, strength, dosage form and pack size before ordering. As this is a prescription medicine, use it only according to your doctor’s instructions.
You can also compare related Nintedanib 100mg Capsule information available on 24x7Pharma. For another strength, see Nintedanib 150mg Capsule.
For additional treatment options, browse the Idiopathic Pulmonary Fibrosis medicine collection at 24x7Pharma.
Why Choose 24x7Pharma?
24x7Pharma provides online access to prescription medicines and detailed product information. Before placing an order for Nintena 100mg, customers should confirm that the product matches their prescription.
- Detailed product information
- Clear composition and strength details
- Prescription medicine information
- Convenient online ordering
- Access to related respiratory medicines
Frequently Asked Questions About Nintena 100mg Capsule
What is Nintena 100mg Capsule?
Nintena 100mg Capsule contains Nintedanib 100mg. It is a prescription tyrosine kinase inhibitor used for certain fibrosing lung diseases in adults.
What is Nintena 100mg used for?
Nintena 100mg may be prescribed for idiopathic pulmonary fibrosis and certain chronic fibrosing interstitial lung diseases with a progressive phenotype. Other uses depend on the applicable local prescribing information and specialist assessment.
What is the composition of Nintena 100mg?
Nintena 100mg contains Nintedanib 100mg as the active ingredient.
Is Nintena 100mg a prescription medicine?
Yes. Nintena 100mg is a prescription medicine and should be used under medical supervision.
How does Nintena 100mg work?
Nintedanib blocks several tyrosine kinase signalling pathways involved in fibrosis and abnormal tissue growth. This can help slow disease progression in eligible patients.
Should Nintena 100mg be taken with food?
Yes. Nintedanib capsules should be taken with food and swallowed whole with liquid.
Can Nintena 100mg be crushed?
No. The capsule should be swallowed whole. It should not be crushed, opened or chewed.
What is the usual dose of Nintena 100mg?
The dose depends on the medical condition, liver function and treatment response. A 100mg dose may be used in certain clinical situations. Your doctor should decide the exact dose.
What happens if I miss a Nintena 100mg dose?
Take the next dose at the scheduled time. Do not take an extra dose to compensate for the missed capsule.
What are the common side effects of Nintena 100mg?
Common side effects may include diarrhea, nausea, vomiting, abdominal discomfort, reduced appetite, weight loss, headache and increased liver enzymes.
Can Nintena 100mg affect the liver?
Yes. Nintedanib can increase liver enzymes and may cause liver injury. Your doctor may recommend liver function tests before and during treatment.
Can Nintena 100mg cause diarrhea?
Yes. Diarrhea is a common adverse effect of nintedanib. Severe or persistent diarrhea should be reported to your healthcare professional.
Can Nintena 100mg be taken during pregnancy?
Nintedanib may harm an unborn baby. Discuss pregnancy prevention with your doctor before starting treatment and contact your doctor immediately if pregnancy occurs.
Can I breastfeed while taking Nintena 100mg?
Discuss breastfeeding with your doctor before using Nintena 100mg. Your healthcare professional will assess the potential risks and benefits.
Does Nintena 100mg interact with other medicines?
Yes. Several medicines can affect nintedanib exposure. Tell your doctor about all prescription medicines, over-the-counter products, vitamins and supplements.
Can Nintena 100mg cure pulmonary fibrosis?
No. Nintedanib does not remove established lung scarring. It is used to help slow disease progression and the decline in lung function in approved conditions.
How should Nintena 100mg be stored?
Store the medicine according to the product label. Indian medicine listings advise storage below 25°C. Keep the capsules protected from heat, moisture and direct sunlight.
Does Nintena 100mg require blood tests?
Your doctor may recommend liver function tests and other monitoring during treatment. The exact monitoring schedule depends on your medical condition.
Can I stop Nintena 100mg when I feel better?
No. Do not stop treatment without discussing it with your doctor. Your healthcare professional will decide whether treatment should continue or change.
Who should prescribe Nintena 100mg?
Nintena 100mg should be prescribed by a qualified healthcare professional after assessing your diagnosis, medical history and treatment requirements.
What should I do in case of Nintena 100mg overdose?
If you take more than the prescribed amount, contact a healthcare professional or seek urgent medical attention. Do not take additional doses to compensate for a missed dose.
Medical Disclaimer
Disclaimer: Nintena 100mg Capsule is a prescription medicine. The information provided on this page is intended for general educational and product-information purposes only. It does not replace medical advice, diagnosis or treatment. Always use Nintena 100mg exactly as prescribed by your healthcare professional. Do not start, stop or change the dose without medical advice.
