About PALBACE 125mg Capsule
PALBACE 125mg Capsule belongs to the group of anti-cancer drugs used to treat certain types of breast cancer. Cancer is the uninhibited and uncontrolled growth of cells in the body. Breast cancer is cancer that forms in the cells of the breast. It can form in the lobules, ducts or tubules of the breast or in the breast tissue itself.
PALBACE 125mg Capsule contains Palbociclib that works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, PALBACE 125mg Capsule is effective in controlling cancer cells from multiplying and is used in the treatment of breast cancer.
Take PALBACE 125mg Capsule as prescribed. In some cases, PALBACE 125mg Capsule may cause certain common side effects such as weakness, loss of appetite, infections and dry skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.
It is advisable to inform the doctor if you are allergic to any of its components. Do not take PALBACE 125mg Capsule if you are pregnant or breastfeeding. PALBACE 125mg Capsule may cause tiredness, so drive only if you are alert. PALBACE 125mg Capsule is not recommended for use in children below 18years. Keep your doctor informed about your health condition and medications to rule out any interactions.
Uses Of PALBACE 125mg Capsule
- Breast Cancer
Medicinal Benefits
PALBACE 125mg Capsule is an anti-cancer drug used in the treatment of a particular type of breast cancer that is hormone receptor-positive and human epidermal growth factor receptor-2-negative. PALBACE 125mg Capsule works by blocking the production of proteins called cyclin-dependent kinase 4 and 6 that are responsible for cell growth and division. By blocking them, PALBACE 125mg Capsule nips cell growth in the bud and prevents cancer cells from spreading further. Thus, PALBACE 125mg Capsule helps treat breast cancer.
Directions For Use
Storage
- Store in a cool and dry place away from sunlight
Side Effects Of PALBACE 125mg Capsule
- Loss of appetite
- Dry skin
- Weakness
- Infection
- Hair loss
- Fever
- Inflammation of the mouth and lips
Precautions And Warning
Do not take St. John’s wort or grapefruit/grapefruit juice with PALBACE 125mg Capsule. It is advisable to inform the doctor if you are allergic to any of its components. Do not take PALBACE 125mg Capsule if you are pregnant or breastfeeding. PALBACE 125mg Capsule may cause tiredness, so drive only if you are alert. PALBACE 125mg Capsule is not recommended for use in children below 18years. If you experience any signs or symptoms of infections, inform your doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Consult your doctor immediately if you experience symptoms such as dry cough, chest pain, difficulty breathing or shortness of breath as it could be an indication of lung inflammation
Interactions
DrugInteractions: PALBACE 125mg Capsule may interact antiviral/anti-HIV drug (lopinavir, ritonavir, nelfinavir, telaprevir, saquinavir), antidepressant (St John’s wort and nefazodone), antifungals (voriconazole, itraconazole, ketoconazole, posaconazole), antibiotics (clarithromycin, telithromycin) anti-rheumatoid drug (abatacept), heart medicine (quinidine), anti-gout medicine (colchicine), anaesthetics (alfentanyl and fentanyl), immunosuppressants (tacrolimus, cyclosporine), antipsychotics (pimozide) and anti-migraine drugs (dihydroergotamine, ergotamine).
Food Interactions: PALBACE 125mg Capsule may interact with grapefruit and grapefruit juice.
Disease Interactions: PALBACE 125mg Capsule should be used with caution in patients with a known hypersensitivity disorder, HIV, epilepsy, lactose intolerance, kidney disease, liver disease, lung or breathing disorders, hypertension, diabetes, heart disease, gout or a disease of the veins.
Drug Interactions
- Ritonavir
- Nelfinavir
- Saquinavir
- Lopinavir
- Telaprevir
- Itraconazole
- Ketoconazole
- Voriconazole
- Posaconazole
- Clarithromycin
- Telithromycin
- Abatacept
- Quinidine
- Colchicine
- Alfentanil
- Fentanyl
- Tacrolimus
- Cyclosporine
- Pimozide
- Ergotamine
Safety Advice
Alcohol
It is not recommended to use alcohol with PALBACE 125mg Capsule. Please consult your doctor if you have any concerns.
Pregnancy
PALBACE 125mg Capsule is not recommended for use in pregnancy. Please consult your doctor if you have any concerns.
Breast Feeding
PALBACE 125mg Capsule is not recommended during breastfeeding. Please consult your doctor in case of any concerns.
Driving
PALBACE 125mg Capsule may cause tiredness and lethargy, which may affect your ability to drive. Do not drive if you experience any side effects after using PALBACE 125mg Capsule.
Liver
Exercise caution before using PALBACE 125mg Capsule in case of established liver disease. Please consult your doctor to address any concerns.
Kidney
Exercise caution before using PALBACE 125mg Capsule in case of established kidney disease. Please consult your doctor to address any concerns.
Children
PALBACE 125mg Capsule is not recommended for use in children under 18 years of age. Please consult your doctor in case of any concerns.
Diet & Lifestyle Advise
- Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
- Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy.
- Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.
- Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired.
- Avoid smoking and alcohol consumption.
Special Advise
- Discuss contraception with your doctor while taking PALBACE 125mg Capsule.
- People on treatment with PALBACE 125mg Capsule should use additional contraception (barrier method such as condoms). Contraception should be continued 3 weeks post-treatment for women and 14 weeks post-treatment for men.
- You may want to consider sperm storage before starting PALBACE 125mg Capsule. Seek counsel on the same from a qualified healthcare individual and/or sperm bank.
- Regular complete blood count monitoring is advised.
