PTH 30MG contains cinacalcet which belongs to a group of medicines called calcimimetic agent that increases the sensitivity of the calcium-sensing receptor to activation by extracellular calcium. It treats problem with the organs called parathyroid glands. The parathyroids are four small glands in the neck, near thyroid gland, that produce the parathyroid hormone (PTH). Hyperparathyroidism (HPT) is a condition where the parathyroid gland may become overactive and make too much PTH. In this condition the calcium stored in the bones move into the blood leading to hypercalcemia (too much calcium in the blood).
Secondary hyperparathyroidism (SHPT) describes an alteration in bone and mineral metabolism that occurs as a direct result of chronic kidney disease (CKD). The parathyroid gland is the central organ responsible for regulating these adaptive responses leading to secondary hyperparathyroidism. Parathyroid hormone helps prevent low calcium levels by acting on the bones, intestine, and kidneys. PTH 30MG works by controlling levels of the parathyroid hormone (PTH), calcium and phosphorous in body.
Children under the age 18 with parathyroid cancer or primary hyperparathyroidism must not take this medicine. Do not drive or operate machines, if you experience side effects such as dizziness and seizures. If you are pregnant or breast-feeding, think you may be pregnant or planning to have a baby, ask your doctor for advice before taking this medicine. The usual starting dose for this medicine in adults is 30 mg twice per day or as directed by your physician. Swallow the medicine whole with plenty of water. The most common side effects are nausea, vomiting, dizziness, rash, muscle pain, loss of appetite, headache, etc.
USES OF PTH 30MG:
Secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on dialysis
Hypercalcemia in patients with Parathyroid carcinoma and primary hyperparathyroidism (HPT)
HOW PTH 30MG WORKS:
PTH 30MG works by controlling levels of the parathyroid hormone (PTH), calcium and phosphorous in body.
DIRECTIONS FOR USE:
The usual starting dose for this medicine in adults is 30 mg twice per day or as prescribed by your doctor. Swallow the medicine whole with plenty of water.
SIDE EFFECTS OF PTH 30MG:
• Numbness or tingling around mouth, muscle aches or cramps and seizures. These may be signs of low calcium levels (hypocalcaemia)
• Swelling of face, lips, mouth, tongue or throat which may cause by difficulty in swallowing or breathing (angioedema)
• Dizziness, headache
• Nausea or vomiting
• Feeling weak
• Loss (anorexia) or decrease of appetite
• Muscle pain (myalgia)
• Weakness (asthenia)
• Reduced testosterone levels
• High potassium levels in the blood (hyperkalaemia)
• Allergic reactions (hypersensitivity)
HOW TO MANAGE SIDE EFFECTS:
Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.
Nausea and vomiting:
Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
WARNING & PRECAUTION:
PTH 30MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
PTH 30MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate any machinery while taking this medicine, it may make you feel dizziness, seizures.
Consumption of alcohol is not recommended during treatment with this medicine.
PTH 30MG should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
PTH 30MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
Do not take if you are allergic to the medicine.
If you have any heart related problems, consult your doctor for advice before taking this medicine.
Do not take PTH 30MG if you have low levels of calcium in your blood.
Talk to your doctor if you are taking medicines used to:
Treat the skin and fungal infections
Treat the bacterial infections (telithromycin, rifampicin and ciprofloxacin)
Treat HIV infection and AIDS (ritonavir)
Treat depression (fluvoxamine)
Relieve cough (dextromethorphan)
Treat the changes in heart rate (flecainide and propafenone)
Treat high blood pressure
Drug : Cinacalcet
Pharmacological Category : Calcimimetics
Therapeutic Indication : Hyperparathyroidism
Dosage Forms : Tablet
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT PTH 30MG:
Q: Can PTH 30MG be used in pregnant women?
A: No. It is not recommended for use in the pregnant women. Consult your doctor before taking.
Q: Does PTH 30MG cause hypocalcemia?
A: It can cause acute, severe and symptomatic hypocalcaemia in susceptible patients, possibly those with prolonged high bone turnover states or those not receiving VDRA therapy.
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