Primovir Tablet Nirmatrelvir 150 mg & Ritonavir 100 mg

Introduction of Primovir Tablet Nirmatrelvir 150 mg & Ritonavir 100 mg: 

Primovir Tablet is a combination of two medications containing Nirmatrelvir 150 mg and Ritonavir 100 mg. It is an oral drug generally prescribed authorised for emergency use to deal with mild to moderate level of COVID-19 viral infection  in adults and paediatric patients, with proven positive results of direct SARS-CoV-2 testing , and who are at high risk factor for progressing to severe COVID-19 infection, which includes hospitalisation or death. Nirmatrelvir 150 mg medicine is available in the form of tablets and is taken with Ritonavir 100 mg to increase the plasma levels of Nirmatrelvir to increase its therapeutic effect.

Understanding the Working Mechanism of Nirmatrelvir 150 mg Tablet: 

The first component of Primovir Tablet is Nirmatrelvir 150 mg which works as a potent inhibitor of the main protease (Mpro) enzyme of coronaviruses. It helps by targeting Mpro, Nirmatrelvir 150 mg decreases the viral replication process.

Ritonavir 100 mg is the second component of Primovir Tablet, which is a pharmacokinetic enhancer, it is combined with Nirmatrelvir 150 mg to increase its bioavailability and prolong its presence in the bloodstream of our body. Ritonavir 100 mg ensures a sustained antiviral activity by slowing down the metabolism of Nirmatrelvir 150 mg to increase the efficacy of the combination of therapy.

Indications for Administration and Dosage of Primovir Tablet Nirmatrelvir 150 mg & Ritonavir 100 mg: 

Indications:

Primovir Tablet Nirmatrelvir 150 mg & Ritonavir 100 mg tablet  is recommended for the treatment of low level to high level of COVID-19 coronavirus in adult patients who have a positive result of direct SARS-CoV-2 testing and are at high risk for increment to critical condition of COVID-19 which including death or hospitalisation.

Dosage : 

The recommended dosage of Primovir Tablet basically depends on your body weight. It is important to follow the prescribed dosage and duration of course as directed by your healthcare provider. Generally, Primovir Tablet is taken with or without food orally with a glass of water.

Side Effects of Using Nirmatrelvir 150 mg  & Ritonavir 100 mg tablet :

Here is a list of possible side effects associated with the use of medicine.

1. Nausea
2.  Headache
3. Dizziness
4. Elevated liver enzymes
5. Diarrhoea
6. Rash
7. Hyperbilirubinemia

In rarer cases some individuals may experience such a side effect. Consult with your health care professional, If you experience any  adverse reaction after using medicine.

 Precautionary Steps for Ritonavir 100 mg : 

• It is essential to consult with your healthcare provider before using any new medicine into your daily routine especially when you are using any other medicines, herbals and supplements.
• It is advisable to connect Open and transparent communication with your doctor to discuss any concerns, side effects, or sudden changes in your health status promptly.
• It is advisable to regularly monitor kidney and liver function especially, for those individuals who are dealing with pre-existing kidney or liver problems.

Alternatives

Primovir tablets have alternatives medicine:

• Paxista Tablet
• Paxzen Tablet

Safety Checklist Before Using  Nirmatrelvir 150 mg  & Ritonavir 100 mg: 

Before using this medication, consult your doctor about your medical history, especially of:

• Cardiovascular disease
• Kidney disease
• HIV infection
• Allergic reaction

Alcohol Interaction: It is advisable not to consume alcohol while using Nirmatrelvir 150 mg because alcohol can interact with the effectiveness of drugs and increase the risk factor for side effects.

Pregnancy and Lactation: This medicine is not recommended for use in pregnancy and lactation , because it may interact with other medications and cause side effects, so careful consideration may be required. 

Driving consideration : This medicine can make you feel sleepy and lower your blood sugar level,  then it is advisable to avoid driving and operating heavy machinery.

Heart and Liver Diseases: If you are dealing with any heart and liver diseases then it is unsafe to use medication. Consult with your health care provider before using the medication.

Storage Information: 

• Store in the cool dry place away from moisture and direct sunlight.
• Keep Away from Childrens and Pets.