PRODUCT INTRODUCTION
Paxista Tablet is intended to treat mild-to-moderate coronavirus disease(COVID-19) in adults and children aged 12 years and older weighing at least 40 kg with a positive COVID-19 test and at risk of progression to severe disease. It reduces the ability of the coronavirus to multiply in the body.
Paxista Tablet works by stopping the virus from making copies of itself from being effective, it needs to be started within five days of developing COVID symptoms. It is meant for oral intake regardless of the meals. Stick to the dose and duration as prescribed by the doctor. Do not withdraw it abruptly, even if the symptoms improve within the initial few days of the ingestion and report if it worsens after five days. Complete the medicine course as prescribed. Never self-medicate at home based on symptoms without a confirmatory covid-19 test and the doctor’s prescription.
Some transient side-effects of Paxista Tablet include dysgeusia (altered taste), diarrhea, hypertension, myalgia (muscle pain) and vomiting. Consult the doctor right away in case of worrisome episodes.
Inform the doctor about your complete medical history, including the use of concomitant medicines, allergies, pregnancy, history of liver disease including hepatitis C, immunocompromised conditions such as Human Immunodeficiency Virus(HIV), nursing, surgery, neurological, cardiovascular, or any other underlying medical condition. This will help the doctor formulate the treatment plan in a better way.
Tell the doctor if using combined hormonal contraceptives as Paxista Tablet may affect how the birth control pills work. Females with reproductive potential should practice other effective alternative contraceptive methods. Discuss with the doctor the use of the right contraceptive methods while taking this medication. Additionally, if taking ritonavir-containing medicines for hepatitis C, or HIV, continue taking Paxista Tablet as prescribed.
USES OF PAXISTA TABLET
- Treatment of Coronavirus disease (COVID-19)
BENEFITS OF PAXISTA TABLET
In Treatment of Coronavirus disease (COVID-19)
Paxista Tablet is most helpful for people with mild COVID symptoms who are at high risk of developing severe disease. Nirmatrelvir, an antiviral medicine, stops the virus from spreading into the body, and ritonavir, a booster, increases the availability of nirmatrelvir in the body to maximize the effectiveness of this combination medicine.
SIDE EFFECTS OF PAXISTA TABLET
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Paxista
- Taste change
- Diarrhea
- Vomiting
- High blood pressure
- Muscle pain
HOW TO USE PAXISTA TABLET
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Paxista Tablet may be taken with or without food, but it is better to take it at a fixed time.
HOW PAXISTA TABLET WORKS
Paxista Tablet is a combination of two drugs, nirmatrelvir, a SARS-CoV-2-3CL protease inhibitor and ritonavir, the HIV antiretroviral. Nirmatrelvir blocks the action of SARS-CoV-2-3CL protease enzyme, which is essential for replication of the virus. On the other hand, ritonavir prevents the breakdown of nirmatrelvir.
SAFETY ADVICE
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Paxista Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Paxista Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Paxista Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Paxista Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Paxista Tablet should be used with caution in patients with kidney disease. Dose adjustment of Paxista Tablet may be needed. Please consult your doctor.
The appropriate dosage for patients with severe renal impairment has not been determined. Until more data are available, Paxista Tablet is not recommended in patients with severe renal impairment.
Liver
SAFE IF PRESCRIBED
Paxista Tablet is safe to use in patients with liver disease. No dose adjustment of Paxista Tablet is recommended.
No data are available regarding the use of Paxista Tablet in patients with severe hepatic impairment; therefore, Paxista Tablet is not recommended for use in patients with severe hepatic impairment.
