INTRODUCTION TO CIDIGLIM M2
Cidiglim M2 is a combination of Glimepiride, and Metformin which belongs to a group of medicines called antidiabetic agents. It is used to treat type II diabetes mellitus when diet, exercise, and treatment with other single agents did not result in adequate response. Type II diabetes mellitus is a chronic medical condition in which the body cannot properly utilize the circulating sugars (glucose) from the blood to make energy. As a result, the patient experience sudden unintentional weight loss, extreme tiredness, increased urination, thirst or hunger, and slow healing ulcers. If left untreated, it can cause permanent damage to the nerves in the body, and may to lead to other life-threatening complications.
Glimepiride is a sulfonylurea which acts by making the pancreas secrete more insulin to digest the circulating glucose, and metformin is biguanide which acts by blocking the production of glucose by the liver. CIDIGLIM M2 decrease blood glucose levels, and makes the body respond better to insulin.
While taking Cidiglim M2, patients must continue to take carbohydrate-regularized diet as instructed by their doctor to obtain better results. Before taking Cidiglim M2 inform you’re doctor if you have type 1 diabetes mellitus, severe liver or kidney diseases, or heart problems. Cidiglim M2 is not recommended for use in pregnant, and breastfeeding women. The common side effects of Cidiglim M2 are nausea, vomiting, diarrhea, stomach pain, and changes in taste.
USES OF CIDIGLIM
- Treat type II diabetes mellitus when diet, exercise, and other single agents does not provide adequate response
HOW CIDIGLIM M2 WORKS
CIDIGLIM M2 effectively reduces elevated blood glucose levels, where glimepiride acts by making the pancreas secrete more insulin to digest the circulating glucose, and metformin acts by blocking the production of glucose by the liver. They collectively decrease the elevated blood glucose levels, and makes the body respond better to insulin.
OTHER DOSAGES
DIRECTIONS FOR USE
Take CIDIGLIM M2 as instructed by you’re doctor. Swallow it as whole, and do not crush or chew it. Do not stop taking CIDIGLIM M2 unless you’re doctor tells you to stop.
SIDE EFFECTS OF CIDIGLIM M2
COMMON SIDE EFFECTS
- Nausea, vomiting
- Diarrhea, stomach pain, loss of appetite
- Changes in taste
RARE SIDE EFFECTS
- Low blood sugar levels
- Changes in blood counts (increased tendency to bleed, increased infections, weakness, pale skin)
- Stop taking CIDIGLIM M2 and consult you’re doctor immediately, if you experience
- Signs of lactic acidosis (such as generalized weakness, and tiredness, vomiting, stomach pain, muscle pain, difficulty in breathing, reduced body temperature, and decreased heartbeat)
- Signs of dehydration (such as severe vomiting, diarrhea, fever,
exposure to heat) - Signs of liver problems (such as liver inflammation leading to yellowing of eyes, and skin)
- Signs of allergic reaction (such as skin rash, itching, inflammation of blood vessels, difficulty in breathing, decrease in blood pressure, shock, increased sensitivity to sun)
- Severe hypoglycemia which may cause unconsciousness, seizures, or coma
HOW TO MANAGE SIDE EFFECTS
Nausea and vomiting:
Try to take Cidiglim M2 with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. This side effect can be seen usually while taking Cidiglim M2 and would stop within two weeks of therapy. However, consult you’re doctor if they persist longer.
Diarrhea:
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. This side effect can be seen usually while taking Cidiglim M2 and would stop within two weeks of therapy. However, consult you’re doctor if they persist longer
Low blood sugar:
During signs of low blood sugar levels, immediately consume a meal or a snack which is rich in sugars like sweets, biscuits, or fruit juice. Follow the carbohydrate-regularized diet as instructed by you’re doctor to obtain better results. Consult you’re doctor if the signs of low blood sugar levels do not improve.
WARNING & PRECAUTIONS
PREGNANCY
Cidiglim M2 is generally not recommended for use in pregnant women. Consult you’re doctor before taking.
BREASTFEEDING
Cidiglim M2 is generally not recommended for use in breastfeeding women. Consult you’re doctor before taking.
DRIVING AND USING MACHINES
Do not drive or operate any tools or machines if you experience signs of low blood sugar levels (like dizziness or fainting) while taking Cidiglim M2.
ALCOHOL
Avoid alcohol consumption while taking Cidiglim M2 as it could further increase blood glucose levels.
KIDNEY
Cidiglim M2 is not recommended for use in patients who have severe kidney impairment. Consult you’re doctor before taking.
LIVER
Cidiglim M2 is not recommended if you have severe liver disease. Consult you’re doctor before taking.
ALLERGY
Do not take Cidiglim M2 if you are allergic to Metformin, Glimepiride or other sulphonylureas (such as glibenclamide, gliclazide) or sulfonamides (Ex. sulfamethoxazole).
LUNGS
Cidiglim M2 is not recommended for use in patients having severe infection in the lungs or in the respiratory tract. Consult you’re doctor before taking.
OTHERS
Cidiglim M2 is not recommended for use if you:
- Have metabolic acidosis (buildup of acids or ketone bodies in the body which can cause sever weakness, dizziness, nausea, stomach pain, muscle pain which could be fatal)
- Have diabetic coma (high blood glucose levels causing unconsciousness)
- Have severe dehydration, severe infection, or shock
- Have uncontrollable diabetes or type I diabetes (insulin-dependent diabetes)
Before taking Cidiglim M2, inform you’re doctor if you:
- Recently had an injury, operation, fever with infections or under any other stressful condition
- Malnourished or not eating you’re meals properly (irregular mealtime or skipped meals)
- Recently made changes in you’re diet
- Have hormonal imbalance (Ex. thyroid disorders)
- Are doing high intensity exercises without proper energy-rich nutrient diet
- Are scheduled for a surgery
Use in Pediatrics:
- Cidiglim M2 is generally not recommended for use in children, and adolescents under 18 years of age. Kindly consult you’re doctor before taking.
Use in Geriatrics:
- Cidiglim M2 should be used with caution in elderly patients. Kindly consult you’re doctor before taking.
INTERACTIONS
A. Drug – Drug interactions:
Before taking Cidiglim M2, inform you’re doctor if you are taking,
- Medicines used to treat pain, and inflammation (such as aspirin, ibuprofen, celecoxib, oxyphenbutazone, phenylbutazone, azapropazone)
- Other medicines used to treat diabetes (such as insulin, glyburide)
- Anabolic (used to increase muscle buildup) Ex. nandrolone, oxymetholone
- Medicines used for blood thinning (Ex. warfarin)
- Fenfluramine (used to treat obesity)
- Medicines used to heart problems (Ex. captopril, enalapril, propranolol, disopyramide, methyldopa, clonidine, reserpine, diazoxide)
- Diuretics (used to increase urine output) Ex. hydrochlorothiazide, furosemide
- Medicines used to treat high blood cholesterol levels (Ex. clofibrate, fenofibrate, nicotinic acid, colesevelam)
- Medicines used to treat depression (such as isocarboxazid, phenelzine, selegiline, tranylcypromine, fluoxetine, citalopram).
- Medicines used to treat gout (Ex. allopurinol, probenecid, sulfinpyrazone)
- Medicines used to treat certain forms of cancer (Ex. crizotinib, olaparib trofosfamide, cyclophosphamide, ifosfamide)
- Medicines to treat bacterial infections (Ex. doxycycline, chloramphenicol, azithromycin, erythromycin, clarithromycin)
- Fluconazole, isavuconazole, miconazole (used to treat fungal infections)
- Tritoqualine (used to treat nasal congestion caused due to allergic reactions)
- Pentoxifylline (used to treat circulatory disorders)
- Medicines used to treat urinary tract infections (Ex. cotrimoxazole)
- Testosterone (used to regulate male hormone in the body)
- Estrogen, and progesterone containing medicines (used to regulate female hormones in the body)
- Levothyroxine (used to treat thyroid deficiency)
- Corticosteroids (used to treat pain, and inflammation) Ex. prednisolone, dexamethasone, betamethasone
- Medicines used to treat mental illness (Ex. chlorpromazine, mesoridazine, fluphenazine)
- Medicines that have stimulatory effects in the body (Ex. adrenaline, amphetamine)
- Medicines to treat constipation (Ex. lactulose)
- Phenytoin (used to treat epilepsy)
- Glucagon (used to treat severe low blood sugar levels)
- Barbiturates (used to induce sleep) Ex. phenobarbital
- Rifampicin (used to treat tuberculosis)
- Acetazolamide (used to treat glaucoma)
- Ranitidine, cimetidine (used to treat stomach ulcers)
- Injection of contrast medium (used for diagnostic purpose)
- Dolutegravir (used to treat viral infections)
- Ranolazine (used to treat chest pain)
- Vandetanib (used to treat tumors of thyroid gland)
Over dosage:
If you or anyone else accidentally take too much of CIDIGLIM M2, consult you’re doctor immediately. Overdose may cause signs of lactic acidosis (such as generalized weakness, and tiredness, vomiting, stomach pain, muscle pain, difficulty in breathing, reduced body temperature, and decreased heartbeat).
MORE INFORMATION
- Keep Cidiglim M2 out of reach of children.
- Store Cidiglim M2 at room temperature.
FAQs ABOUT CIDIGLIM M2
1. Can I consume alcohol while taking Cidiglim M2?
Ans. No. Do not consume alcohol while taking CIDIGLIM M2 as it can increase you’re blood sugar levels further.
2. Can Cidiglim M2 cause vitamin B12 deficiency?
Ans. Yes. The use of CIDIGLIM M2 can cause alternation in blood count. It can cause decrease in number of red blood cells making you’re skin look pallor, and can make you feel tired, and weak. Consult you’re doctor if you experience any of these symptoms.
3. What are the possible side effects of Cidiglim M2?
Ans. CIDIGLIM M2 can cause nausea, vomiting, diarrhea, stomach pain, and changes in taste sensation. However, these side effects are usually temporary, and gets resolved within two weeks of time. If they persist for longer period, contact you’re doctor.
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