Peripheral hypertension is a condition that occurs when high blood pressure remains untreated over a prolonged period of time. Also known as high blood pressure, it causes additional strain of the arteries of upper and lower limbs by narrowing the blood vessels.
Peripheral arterial disease (PAD) causes considerable morbidity and mortality. Hypertension is a risk factor for PAD. Treatment for hypertension must be compatible with the symptoms of PAD. Controversy regarding the effects of beta‐adrenoreceptor blockade for hypertension in patients with PAD has led many physicians to stop prescribing beta‐adrenoreceptor blockers. Little is known about the effects of other classes of anti‐hypertensive drugs in the presence of PAD. This is the second update of a Cochrane review first published in 2003.