INTRODUCTION:
Xarelto 2.5mg contains rivaroxaban which belongs to the group of medicines called anticoagulants. It is always used in combination with acetylsalicylic acid and/or clopidogrel to reduce the risk of heart attack and other risk factors of dying in adult patients with acute coronary syndrome, coronary artery disease (CAD) or symptomatic peripheral artery disease (PAD) at high risk of ischemic events.
Xarelto 2.5mg acts by blocking the activity of blood clotting factor (factor Xa) and reduces the tendency of the blood to form clots. This medicine must be taken only with meals. The most common side effects of taking this medicine are bleeding in eyes, nose, gums, stomach, rectum or vagina.
Do not take Xarelto 2.5mg, if you have any bleeding disorders. Before taking this medicine inform your doctor if you are pregnant, breastfeeding or having any serious kidney or liver disease. This medicine is not recommended for use in children and adolescents under 18 years of age.
USES OF XARELTO 2.5MG:
Prevents heart attack and other risk factors of dying in patients with acute coronary syndrome, coronary artery disease (CAD) or symptomatic peripheral artery disease (PAD) at high risk of ischemic events
HOW XARELTO 2.5MG WORKS:
Rivaroxaban reversibly inhibits both the free- and clot-bound forms of coagulation factor Xa. Inhibition of Xa, prevents the conversion of prothrombin into thrombin, which activates platelets and catalyzes the conversion of fibrinogen to fibrin thread (clot) and thus prevents blood clot formation.
DIRECTIONS FOR USE:
Take Xarelto 2.5mg as directed by your physician. It can be taken with or without meals. Your doctor will decide the correct dose for you depending upon your condition. Swallow the medicine as whole with a glass of water. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.
SIDE EFFECTS OF XARELTO 2.5MG:
SERIOUS
• Long or excessive bleeding
• Skin reactions (such as skin rash, blisters or mucosal lesions, swelling of face, lips, mouth, tongue or throat, difficulty in swallowing or breathing, drop in blood pressure)
• DRESS syndrome (fever, rash, inflammation of internal organs, hematologic abnormalities and systemic illness)
COMMON
• Bleeding disorders
• Bruising and swelling
• Anemia, tiredness or paleness
• Coughing up blood
• Pain and swelling in the limbs
• Fever
• Stomach pain, indigestion
• Nausea (feeling sick) or vomiting (being sick)
• Constipation, diarrhea
• Low blood pressure
• Headache, dizziness
• Skin rash
RARE
• Bleeding into a muscle
• Yellowing of skin and eye (jaundice)
HOW TO MANAGE SIDE EFFECTS:
Nausea or vomiting:
Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.
Constipation:
Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.
Diarrhea:
Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.
WARNING & PRECAUTION:
PREGNANCY
Xarelto 2.5mg is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
Xarelto 2.5mg is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate any machines if your ability is affected by this medicine.
ALCOHOL
Avoid consumption of alcohol while taking this medicine.
KIDNEY
Xarelto 2.5mg should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
LIVER
Do not take Xarelto 2.5mg if you have a liver disease which leads to increased risk of bleeding. Consult your doctor for advice.
ALLERGY
Do not take this medicine if you are allergic (hypersensitive) to rivaroxaban.
LUNGS
Xarelto 2.5mg should be taken with caution in patients with previous bleeding from lung or bronchiectasis (bronchi are widened and filled with pus). Consult your doctor for advice.
HEART DISEASE
Xarelto 2.5mg should be taken with caution in patients with prosthetic heart valve or other heart disease. Consult your doctor for advice.
OTHERS
Inform your doctor before taking this medicine, if you have:
Any bleeding disorders
INTERACTIONS:
Talk to your doctor, if you are taking,
Medicines used to treat fungal infections (e.g., ketoconazole, itraconazole, voriconazole, posaconazole)
Medicines used to treat HIV infections (e.g., ritonavir)
Medicines used to treat bacterial infection (e.g. clarithromycin, erythromycin)
Other medicines used to reduce blood clotting (e.g., enoxaparin, warfarin, rivaroxaban, dabigatran or heparin)
Medicines used to reduce pain or inflammation (e.g., acetylsalicylic acid or naproxen)
Medicines used to treat depression (e.g., fluoxetine, sertraline, imipramine, St John?s Wort)
Medicines used to treat epilepsy (e.g., phenytoin, carbamazepine, phenobarbital)
Dronedarone (used to treat abnormal heartbeat)
Rifampicin (used to treat tuberculosis)
SYNOPSIS:
Drug : Rivaroxaban
Pharmacological Category : Anticoagulant
Therapeutic Indication : Blood clot
Dosage Forms : Tablet
MORE INFORMATION:
Store at room temperature and keep out of reach of children.
FAQ’s ABOUT XARELTO 2.5MG:
Q: Can you drink alcohol while taking Xarelto 2.5mg?
A: No. Avoid consumption of alcohol while taking this medicine, as it may make you feel dizzier.
Q: Can you take ibuprofen with Xarelto 2.5mg?
A: No. Avoid concomitant use of this medicine with ibuprofen or any other pain killers without consulting your doctor.
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