INTRODUCTION TO XYZAL M
Xyzal M is a combination of Levocetirizine and Montelukast which belongs to the group of medicines called H₁ receptor antagonists and Leukotriene receptor antagonists respectively. Xyzal M is indicated for the treatment and prevention of allergic rhinitis, chronic idiopathic urticaria allergic skin reaction with red raised itchy bumps on skin) and bronchial asthma in adults and in adolescents (aged 15 years or above).
Allergic rhinitis (also known as hay fever) is a heterogeneous disorder characterized by inflammation of the inner lining of nose accompanied by nasal decongestion, repeated sneezing, wheezing, or a red, watery and itchy eyes.
It is usually caused by allergens such as pollens, dusts, mold or flakes of skin from certain animals and can occur seasonally or year-round. Bronchial asthma is a long-term medical condition in which the path of the airways becomes inflamed, narrow and swollen. Symptoms include coughing, wheezing and chest tightness.
Xyzal M is contraindicated for use in patients having severe kidney impairment. Consult you’re doctor before use. Avoid consumption of alcohol while taking Xyzal M as it could make you feel drowsier.
Xyzal M may cause certain unpleasant neuropsychiatric events (such as anxiety, depression, nightmares, hallucinations or even suicidal thoughts) in some individuals. Contact you’re doctor immediately if you or anyone else experiences such events during treatment with Xyzal M.
The most common side effects of taking Xyzal Mare upper respiratory tract infection, fever, cough, inflammation of the pharynx, dryness of mouth, headache and sleepiness. Consult you’re doctor if any of the side effects worsen.
USES OF XYZAL M TABLET
- Treats and prevents allergic rhinitis, chronic idiopathic urticaria and bronchial asthma in adults and in adolescents (aged 15 years or above)
HOW XYZAL M TABLET WORKS
Xyzal M provides relief from the symptoms of allergic rhinitis, asthma and urticaria where levocetirizine acts by blocking the actions of histamines (a substance that cause allergic reaction), at the H₁ receptors present on the surface of cells and montelukast acts by blocking the action of leukotrienes D4 (an inflammatory molecule causing narrowing and swelling of the airways) in the lungs, thus causing relaxation of smooth muscle, reduction in swelling and/or inflammation of the airways and a marked decrease in the onset of allergic reactions.
DIRECTIONS FOR USE
Take Xyzal M as advised by you’re physician. Swallow Xyzal M with a glass of water. Do not crush or chew the medicine. You’re doctor will decide the correct dose and duration of Xyzal M for you depending upon you’re age, body weight and disease condition.
SIDE EFFECTS OF XYZAL M
COMMON SIDE EFFECTS OF XYZAL M
- Upper respiratory infection
- Cough, cold, fever or flu-like symptoms
- Pharyngitis (inflammation of the pharynx)
- Headache and tiredness
- Dizziness, sleepiness
- Nausea, vomiting, dry mouth, thirst, stomach pain, diarrhea, indigestion
- Otitis media (inflammation or infection of the ears)
- Skin rash
- Bleeding from the nose
- Muscle pain, joint pain
UNCOMMON SIDE EFFECTS OF XYZAL M
- Exhaustion
- Behaviour and mood related changes
- Agitation including aggressive behaviour or hostility
- Seizures
- Dream abnormalities
- Restlessness
- Drowsiness
- Bruising, itching, hives
- Muscle pain, muscle cramps, weakness
- Feeling unwell, swelling
RARE SIDE EFFECTS OF XYZAL M
- Increased bleeding tendency
- Uncontrolled muscle movements
- Angioedema (swelling underneath the skin)
- Palpitations (fast heartbeat)
Stop giving Xyzal M to you’re child and contact doctor immediately if you’re child experiences any of the following side effects:
- Severe allergic reactions (such as skin rash, itching, swelling of the face, eyelids, mouth, throat and neck and difficulty in breathing or swallowing)
- Systemic eosinophilia (increased levels of WBC in blood)
- Vasculitis or Churg-Strauss syndrome (inflammation of the blood vessels)
- Neuropsychiatric disorders (such as agitation, anxiety, depression, disorientation, hyperactivity, nightmares, hallucinations, insomnia, memory impairment, walking in the sleep, tremor, attention disturbance)
- Thoughts of harming or killing yourself (suicidal ideation)
HOW TO MANAGE SIDE EFFECTS
DIARRHEA
Drink lots of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on you’re own for treating diarrhea. Consult you’re doctor if the symptom did not improve.
DIZZINESS OR DROWSINESS
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate you’re dizziness. Consult you’re doctor if the symptom did not improve.
NAUSEA AND VOMITING
Try to take Xyzal M with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult you’re doctor if the symptom did not improve.
STOMACH PAIN
Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on you’re stomach. Do not self-treat on you’re own and consult you’re doctor if the symptom did not improve.
HEADACHE
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much of alcohol. Consult you’re doctor if the symptom did not improve.
WARNING & PRECAUTIONS
PREGNANCY
USE WITH CAUTION
Xyzal M should be used with caution during pregnancy only if considered clearly necessary. Consult you’re doctor before taking Xyzal M.
BREASTFEEDING
USE WITH CAUTION
Xyzal M should be used with caution in breast-feeding. Consult you’re doctor before taking Xyzal M.
DRIVING AND USING MACHINES
USE WITH CAUTION
Do not drive or operate any machines if you experience sleepiness/drowsiness, fatigue or physical weakness. Consult you’re doctor before taking Xyzal M.
ALCOHOL
CONSULT YOU‘RE DOCTOR
Avoid consumption of alcohol while taking Xyzal M as it could cause reduction in alertness and impairment of performance. Consult you’re doctor before taking Xyzal M.
KIDNEY
CONSULT YOU‘RE DOCTOR
Xyzal M is not recommended for use in patients with severe kidney impairment. It should be taken with extreme caution in patients with kidney disease. Consult you’re doctor before taking Xyzal M.
LIVER
USE WITH CAUTION
Xyzal M should be taken with caution in patients with liver disease. Consult you’re doctor before taking Xyzal M.
ALLERGY
CONTRAINDICATED
Do not take Xyzal M if you are allergic to Montelukast or Levocetirizine. Consult you’re doctor before taking Xyzal M.
LUNGS
CONTRAINDICATED
Xyzal M is not recommended for use in patients with asthma attacks. Consult you’re doctor before taking Xyzal M.
OTHERS
XYZAL M TABLET IS NOT RECOMMENDED FOR USE IF YOU:
- Have galactose intolerance (inherited condition in which the body cannot convert galactose to glucose)
- Have Lapp lactase deficiency (deficiency of the enzyme lactase in the body)
- Have glucose-galactose malabsorption
- Have phenylketonuria (release of phenylalanine in urine)
BEFORE TAKING XYZAL M TABLET, INFORM YOU’RE PHYSICIAN IF YOU:
- Have or at risk of having epilepsy
- Have scheduled allergy skin tests
- Have sensitivity to aspirin or other NSAIDs
- Have any predisposing factors of urinary retention (Ex. spinal cord lesion, prostatic hyperplasia)
INTERACTIONS
DRUG-DRUG INTERACTIONS:
Before taking Xyzal M, inform you’re doctor, if you are taking any of the following medicines:
- Gemfibrozil (used to control high blood cholesterol levels)
- CNS depressants (Ex. phenobarbital), phenytoin (used to treat epilepsy)
- Rifampicin (used to treat tuberculosis)
- Ritonavir (a medicine used to treat viral infections)
- Theophylline (a medicine used to treat asthma)
OVERDOSAGE:
If you or anyone else take too much of Xyzal M, contact you’re doctor immediately or go to a hospital straight away. Overdosage symptoms of Xyzal M might include stomach pain, thirst, sleepiness, headache, vomiting, hyperactivity, agitation, excitation and restlessness.
MORE INFORMATION
- Keep Xyzal M out of reach of children
- Store Xyzal M at room temperature
FAQs ABOUT XYZAL M TABLET
Q: How long does it take for Xyzal M to provide relief from symptoms?
A: Following oral administration with Xyzal M, it is believed to provide relief from the symptoms of allergy and asthma within 30 minutes to an hour. Please note that the onset of action varies from product to product and consult you’re doctor if you have any queries.
Q: Can Xyzal M be used to treat acute asthma attacks?
A: No, Xyzal M is used only to prevent asthma attacks. Xyzal M should not be used on an asthma attack that has been started already. Contact you’re doctor or go to the nearby hospital to avoid exacerbation of the attack.
Q: Can Xyzal M be used in infants?
A: No, Xyzal M is only meant to be used in adults and in adolescents (aged 15 years or above). Xyzal M is strictly not recommended for use in children aged between 6 months to 11 years of age without consulting you’re doctor.
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