ZYCEVA 150MG TABLET

About Zyceva 150mg Tablet

Zyceva 150mg Tablet belongs to the group of medicine called ‘anti-cancer’ primarily used for lung and pancreatic cancer treatment. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. These abnormal cells do not carry out normal lung cell functions and do not develop into healthy lung tissue. In this disease, cells of the lung grow uncontrollably, and if not detected at an early stage may spread to other body parts, including the brain. Pancreatic cancer is an uncontrolled cancerous growth in the pancreas, usually in the cells that produce insulin.

Zyceva 150mg Tablet contains ‘Erlotinib’ that belongs to the group of medicines known as ‘kinase inhibitors’. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it prevents the spread of cancerous cells.

Take Zyceva 150mg Tablet as prescribed by your doctor. You are suggested to take Zyceva 150mg Tablet as long as your doctor has prescribed it after checking your medical condition.  In some cases, you may experience certain common side-effects such as abdominal pain, bone pain, breathlessness, constipation, cough, diarrhea, edema (swelling), fatigue, fever, infection, muscle pain, nausea, rash, stomatitis (inflammation of the mouth), vomiting, weight loss abnormal blood tests for the liver function. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking Zyceva 150mg Tablet for as long as your doctor has prescribed. Do not take Zyceva 150mg Tablet if you are pregnant or planning for pregnancy and breastfeeding as Zyceva 150mg Tablet causes serious congenital disabilities. Older adults are more sensitive to medicine so that they may adjust the dosage according to the condition. While taking Zyceva 150mg Tablet, you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF). Regular blood tests are required to monitor liver function and blood cells in the blood while taking Zyceva 150mg Tablet. Avoid consuming alcohol along with Zyceva 150mg Tablet as it could lead to increased dizziness.

Uses Of Zyceva 150mg Tablet

• Lung cancer, Pancreatic cancer

Medicinal Benefits

Zyceva 150mg Tablet is prescribed to the patients dealing with nonsmall cell lung cancer and pancreatic cancer. Cancer of this type tends to spread quickly in other parts of the body. Zyceva 150mg Tablet travel through the bloodstream and effectively destroy cancerous cells of the lung, pancreas, and other body parts. Zyceva 150mg Tablet contains Erlotinib is a ‘tyrosine kinase inhibitor (TKI)’ that stops the uncontrolled growth and spread of cancerous cells. It acts by blocking the abnormal protein’s action that is responsible for the multiplication of cancerous cells. Whenever a new healthy cell is formed, it undergoes a usual process of maturity. Cancerous cells form new cells more quickly, so Zyceva 150mg Tablet targets cancerous cells and block the action of Tyrosine kinases enzymes (responsible for causing cancer). It also decreases the blood supply to cancer tumors to slow down the growth of the tumor. In this way, Zyceva 150mg Tablet stops the production, spread, and growth of cancerous cells in the body.

Directions For Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

• Store in a cool and dry place away from sunlight

Side Effects Of Zyceva 150mg Tablet

• ​​​​Stomach pain
• Bone pain
• Breathlessness
• Constipation
• Cough
• Diarrhea
• Loss of appetite
• Edema (swelling)
• Fatigue
• Fever
• Infection
• Muscle pain
• Nausea
• Rash
• Changes in vision
• Partial hair loss (by strands, not typically in clumps)
• Stomatitis (Inflammation of the mouth)
• Weight loss
• Abnormal blood tests for the liver function

Precautions And Warning

Do not take Zyceva 150mg Tablet if you are allergic to Zyceva 150mg Tablet or any of its ingredients. While taking Zyceva 150mg Tablet, you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF) while going out as it can lead to a skin rash if you are not using a strong SPF. Zyceva 150mg Tablet can cause leg swelling and water retention or fluid overload (edema), so if you have unexpected rapid weight gain, please consult your doctor. Do not take Zyceva 150mg Tablet if you are pregnant or planning to get pregnant and breastfeeding as it could harm the unborn baby. Use effective birth control measures while taking this medication and for at least 1 month after your last dose. Zyceva 150mg Tablet is not recommended for children and adolescents. You are advised to stop smoking while taking Zyceva 150mg Tablet as smoking could decrease this medication’s effect. Zyceva 150mg Tabletmay make you more susceptible to infections, consult your doctor if you develop any signs of infections, fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.  Zyceva 150mg Tablet may cause blurry vision and dizziness, so do not drive or operate any machinery which requires concentration. Before undergoing any surgery, it is advised to tell the medical professional who performs the procedure about all the medicines you are taking.

Interactions

Drug Interaction: Zyceva 150mg Tablet is known to interact with blood thinners (warfarin, aspirin), anti-hypertensive medicines (amlodipine, metoprolol, nifedipine), heart medicines (quinidine, atorvastatin, fluvastatin, pravastatin, rosuvastatin, simvastatin), immuno-suppressants (cyclosporine),  antibiotics (erythromycin, telithromycin, clarithromycin, rifampicin, ciprofloxacin), anti-fungal medicines (itraconazole, voriconazole, ketoconazole), mental illness medicines (triazolam, alprazolam, estazolam, primidone, phenobarbital, phenytoin, phenytoin, carbamazepine), anti-HIV medicines (saquinavir,  ritonavir), erectile dysfunction medicine (sildenafil), antiulcer (omeprazole, ranitidine).

Food Interaction: Zyceva 150mg Tablet is known to interact with alcohol, St. John’s wort plant (a natural remedy to treat depression), and grapefruit.

Disease Interaction: Zyceva 150mg Tablet is known to interact in patients with hypothyroidism (underactive thyroid), cardiovascular disease, bone marrow suppression, liver or kidney disease, fluid retention, gastrointestinal disorders, stomach ulcer or bleeding, high blood pressure, diabetes, and chemotherapy.

Drug Interactions

• Warfarin
• Aspirin
• Amlodipine
• Metoprolol
• Nifedipine
• Quinidine
• Atorvastatin
• Fluvastatin
• Pravastatin
• Rosuvastatin
• Simvastatin
• Cyclosporine
• Erythromycin
• Telithromycin
• Clarithromycin
• Rifampicin
• Ciprofloxacin
• Itraconazole
• Voriconazole
• Ketoconazole
• Triazolam
• Alprazolam
• Estazolam
• Primidone
• Phenobarbital
• Phenytoin
• Carbamazepine
• Saquinavir
• Ritonavir
• Sildenafil
• Omeprazole
• Ranitidine

Safety Advice

Diet & Lifestyle Advise

• ​​​​​​Physical activity helps in strengthening muscles, reduce fatigue, aids in weight loss, and give strength. Gentle exercises like 20-30 minutes of walking or swimming would be helpful.
• Performing yoga and other relaxation techniques may also improve physical and mental health and reduce stress levels.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep as resting helps in improving your health, mental ability and improves attention.
• De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing fiber help in better digestion. These include beans, peas, lentils, whole grains,  nuts, and seeds.
• Avoid smoking and alcohol consumption.

Special Advise

• ​​​​​​Regular blood test is required to monitor liver function and blood cells in blood while taking Zyceva 150mg Tablet.
• While taking Zyceva 150mg Tablet, you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF) while going out as it can lead to a skin rash if you are not using a strong SPF.
• Always take it with food and a full glass of water to prevent nausea.
• Zyceva 150mg Tablet can cause swelling and water retention, so if you have unexpected rapid weight gain, please consult your doctor.
• Do not have immunizations with live vaccines (for mumps, rubella, measles and BCG, yellow fever and shingles or pox chicken) while you’re having treatment and for up to 12 months afterward.
• Contact your doctor immediately if you experience any infection signs, including a temperature above 37.5 C or below 36 C.