Cremagel 2% Gel 30gm

INTRODUCTION:

Cremagel 2% Gel contains diltiazem which belongs to a group of medicines called calcium-channel blockers. It is used to promote healing and reduce the pain in anal fissure. An anal fissure is a small cut or tear that has occurred in the skin inside your anus. Symptoms may include severe and sharp pain, irritation and tenderness. Certain fissures may heal quickly, while others can take several months to heal.

Local application of CREMA 2% causes inhibition of extracellular calcium influx across the smooth muscle cell membranes present on the application site (anus). This reduced intracellular calcium concentrations will increase muscle relaxation and reduces pressure and increases blood flow to the area to allow healing to occur.

The most common side effects of taking this medicine are headache, light-headedness or dizziness, local itching, soreness or rectal bleeding. Your doctor will let you know how long you should continue treatment for. In most cases this will be for six to eight weeks. Apply the gel just inside and around the anus (back passage) as instructed by your doctor. A finger covering such as cling film, disposable glove or finger cot may be used to apply the gel.

USES OF CREMA 2%:

Anal fissure (a tear in the skin of the lower half of the anal canal)

HOW CREMA 2% WORKS:

Local application of CREMA 2% causes inhibition of extracellular calcium influx across the smooth muscle cell membranes present on the application site (anus). This reduced intracellular calcium concentrations will increase muscle relaxation and reduces pressure and increases blood flow to the area to allow healing to occur.

DIRECTIONS FOR USE:

Use the gel twice daily (morning and evening) or as directed by your doctor. It is for external use only. Wash your hands before and after application of the cream to ensure hygiene is maintained. Apply the gel just inside and around the anus (back passage) as instructed by your doctor. A finger covering such as cling film, disposable glove or finger cot may be used to apply the gel.

SIDE EFFECTS OF CREMA 2%:

COMMON

• Headache
• Light-headedness or dizziness
• Local itching, soreness or rectal bleeding

HOW TO MANAGE SIDE EFFECTS:

Headache:

Rest and drink plenty of fluids. Do not drink too much alcohol.

Light-headedness or dizziness:

Try to rest and relax. Eat simple meals. Do not drive or operate any machinery while you are feeling dizzy.

WARNING & PRECAUTION:

PREGNANCY

CREMA 2% should be used with caution in pregnant women. Consult your doctor before using this medicine.

BREASTFEEDING

CREMA 2% should be used with caution in breastfeeding women. Consult your doctor before using this medicine.

DRIVING AND USING MACHINES

Do not drive or operate any tools or machines if your ability is affected by this medicine.

ALLERGY

Do not use this medicine if you are allergic (hypersensitive) to diltiazem or any other ingredients in this medicine.

HEART DISEASE

CREMA 2% should be used with caution in patients having high blood pressure or any other heart disease. Consult your doctor before taking.

INTERACTIONS:

Talk to your doctor, if you are using,

Medicines used to treat high blood pressure such as doxazosin, tamsulosin, atenolol, propranolol or acebutolol
Medicines used to treat angina (such as glyceryl trinitrate or isosorbide trinitrate)

SYNOPSIS:

Drug : Diltiazem
Pharmacological Category : Calcium channel blockers
Therapeutic Indication : Anal fissures
Dosage Forms : Tablet, Capsule, Topical gel, Injection

MORE INFORMATION:

Store CREMA 2% at temperaure not exceeding 25°C

FAQ’s ABOUT CREMA 2%:

Q: Can CREMA 2% cause dizziness?
A: Yes. This medicine can cause dizziness in some individuals, although not everybody gets them. Try to rest and relax. Eat simple meals. Do not drive or operate any machinery while you are feeling dizzy.

Q: What are the uses of CREMA 2%?
A: It is used to treat anal fissure (a tear in the skin of the lower half of the anal canal).