About Abirapro 250mg Tablet
Abirapro 250mg Tablet is an anti-androgen medicine used in the treatment of prostate cancer. It is used to treat metastatic castration-resistant prostate cancer (a condition where cancer does not get controlled with hormonal therapy) and metastatic castration-sensitive prostate cancer (a condition where cancer has spread to other parts of the body but can be controlled) in men. Prostate cancer is a condition that occurs when the prostate gland cells increase abnormally. Symptoms may include difficulty in urinating, pain, numbness, etc.
Abirapro 250mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. Abirapro 250mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.
Abirapro 250mg Tablet may cause certain side effects such as nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite and groin pain. These side effects usually disappear without any medical attention. However, if these side effects persist, inform your doctor. Take this medicine as advised by your doctor. It should be taken on an empty stomach at least 2 hours before or after meals. Your doctor will decide the dose of the medicine based on the severity of your disease.
Abirapro 250mg Tablet should be avoided if you are allergic to it. Inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention before taking Abirapro 250mg Tablet. Abirapro 250mg Tablet is not recommended for use in women and children as the safety and efficacy of this medicine are not established. Inform your doctor of all your ongoing medications to avoid interactions. This medicine is used in combination with prednisolone for the treatment of prostate cancer.
Uses Of Abirapro 250mg Tablet
- Prostate Cancer
Medicinal Benefits
Abirapro 250mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes increase of cancer cells in prostate gland. Abirapro 250mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. Abirapro 250mg Tablet is used in combination with prednisolone for the treatment of prostate cancer. It is mainly intended for use in men only.
Directions For Use
Storage
- Store in a cool and dry place away from sunlight
Side Effects Of Abirapro 250mg Tablet
- Dizziness
- Heartburn
- Headache
- Diarrhoea
- Muscle Weakness
- Joint Pain
- Confusion
- Hot Flushes
- Loss of Appetite
- Groin Pain
Precautions And Warning
Abirapro 250mg Tablet should be avoided if you are allergic to it or any other components present in it. Inform your doctor if you have/had any conditions like liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention or taking any other medicines before taking Abirapro 250mg Tablet as it may cause serious side effects. Abirapro 250mg Tablet is not recommended for use in women and children as the safety and efficacy of this medicine are not established. This medicine is used in combination with prednisolone for the treatment of prostate cancer.
Interactions
Drug interactions: Abirapro 250mg Tablet may interact with CYP3A4 Inducers (phenytoin, phenobarbital), CYP2D6 Substrates (Flecainide, Venlafaxine), antifungal medicine (ketoconazole, itraconazole), and many other medicines.
Food interactions: No interactions found.
Disease interactions: Abirapro 250mg Tablet should be used with caution in patients with severe liver and kidney failure, adrenal or pituitary gland problems, heart failure, an irregular heartbeat, increased blood pressure, adrenocortical insufficiency, and hypoglycemia.
Drug Interactions
- Ketoconazole
- Itraconazole
- Phenytoin
- Phenobarbital
- Flecainide
- Venlafaxine
Safety Advice
Alcohol
Interaction of Abirapro 250mg Tablet with alcohol is unknown. It is advisable to consult your doctor if you have concerns.
Pregnancy
Not intended for women.
Breast Feeding
Not intended for women.
Driving
Abirapro 250mg Tablet may decrease alertness or make you feel sleepy and dizzy. So, do not drive or operate heavy machinery while taking Abirapro 250mg Tablet until your vision improves.
Liver
Abirapro 250mg Tablet should be used with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose based on your condition.
Kidney
Abirapro 250mg Tablet should be used with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust the dose based on your condition.
Children
Abirapro 250mg Tablet is not recommended for use in children as the safety and efficacy of this medicine are not established.
Diet & Lifestyle Advise
- Try to take vegetables like cauliflower, cabbage, broccoli, spinach and kale. This food slows the growth of prostate cancer and even reduces the risk of prostate cancer.
- It is advised to consume fewer dairy products as these foods may increase the risk of prostate cancer.
- Physical activity helps in strengthening muscles, reduces fatigue, helps in weight loss and gives strength.
- Maintain a healthy weight by doing regular simple exercises and yoga.
- Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
- Avoid including red meat high amounts of meat in your diet. When meat is cooked, it may increase the risk of developing prostate cancer.
Special Advise
- Abirapro 250mg Tablet is not recommended for use in patients suffering from severe hepatotoxicity.
- This medicine may cause the laboratory abnormalities like elevated alkaline phosphatase, hypercholesterolemia, hyperglycemia, and hypokalemia.
- It is also advised to perform frequent checkups on your potassium, blood sugar, and blood pressure levels.