About Carmuther 100mg Injection
Carmuther 100mg Injection is a chemotherapeutic medicine used in the treatment of brain tumors. A tumor is defined as the formation of solid mass tissue due to the abnormal growth of cells. A brain tumor is a serious condition where the cells (cancerous or non-cancerous) grow abnormally in the brain. Carmuther 100mg Injection is also used in the treatment of multiple myeloma in combination with prednisone, Hodgkin’s Disease, and non-Hodgkin’s Disease in combination with other approved drugs.
Carmuther 100mg Injection contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.
Carmuther 100mg Injection may cause certain side effects, such as nausea, vomiting, headache, pale skin, dizziness, stomach upset, tiredness, loss of balance, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Carmuther 100mg Injection is a parenteral preparation. A trained healthcare professional will administer it. Hence, do not self-administer.
Carmuther 100mg Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, or respiratory conditions. Carmuther 100mg Injection may cause pulmonary toxicity, bone marrow suppression, gastrointestinal toxicity, nephrotoxicity and hepatotoxicity in some patients. Hence, careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued in nursing mothers during the treatment.
Uses Of Carmuther 100mg Injection
- Brain Tumors, Multiple Myeloma, Hodgkin’s Disease, Non-Hodgkin’s Disease.
Medicinal Benefits
Carmuther 100mg Injection contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.
Directions For Use
Storage
- Store in a cool and dry place away from sunlight
Side Effects Of Carmuther 100mg Injection
- Nausea
- Dizziness
- Stomach upset
- Headache
- Vomiting
- Pale skin
- Tiredness
- Loss of balance
- Diarrhoea
- Cough
- Decreased platelet count
- Bruising or bleeding gums
- Pain at the site of injection
Precautions And Warning
Carmuther 100mg Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, or respiratory conditions. Carmuther 100mg Injection may cause pulmonary toxicity, bone marrow suppression, gastrointestinal toxicity, nephrotoxicity and hepatotoxicity in some patients. Hence careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued in nursing mothers during the treatment. It is unknown whether Carmuther 100mg Injection can be administered in children or not. If administered, close monitoring of the child is needed. Avoid alcohol consumption and smoking as it can lead to serious adverse effects.
Interactions
Drug Interactions: Carmuther 100mg Injection may interact with vaccines, antiretroviral drugs (Abacavir, Zidovudine, adefovir), immunomodulators (abatacept, etanercept), anticoagulants (acenocoumarol, warfarin), anticonvulsant drugs (phenytoin, phenobarbitone).
Food Interactions: Avoid alcohol consumption and smoking.
Disease Interactions: Inform your doctor if you have kidney or liver disease, gastrointestinal disorders, and pulmonary disorders before receiving Carmuther 100mg Injection.
Drug Interactions
- Abacavir
- Zidovudine
- Adefovir
- Abatacept
- Etanercept
- Acenocoumarol
- Warfarin
- Phenytoin
Safety Advice
Alcohol
Avoid alcohol consumption while on treatment with Carmuther 100mg Injection to prevent serious adverse effects.
Pregnancy
Carmuther 100mg Injection is not recommended for use in pregnancy as it may harm your fetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Carmuther 100mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Breast Feeding
Limited data is available on the effect of Carmuther 100mg Injection on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Carmuther 100mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
Carmuther 100mg Injection will be administered in the hospital setting. Hence, avoid driving.
Liver
If you have a pre-existing or a history of liver disease, inform your doctor before receiving Carmuther 100mg Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.
Kidney
If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Carmuther 100mg Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.
Children
Limited information is available for the use of Carmuther 100mg Injection in children. Hence, it will be given to the children only if needed. If administered, careful monitoring of the child is needed.
Diet & Lifestyle Advise
- After your treatment begins, several dietary adjustments can help you control side effects.
- Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
- Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
- Eat a healthy diet and exercise regularly to maintain proper weight.
- Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Get optimal sleep; rest well.
- Avoid smoking and alcohol consumption.
- Avoid fast and fried food, processed meats, refined carbs and added sugars.
Special Advise
- Carmuther 100mg Injection should be administered only by a trained and experienced oncologist.
- A blood test should be performed such as LFT, RFT, and PFT, to check for liver/kidney function, and pulmonary function.
- Weekly blood tests should be done for at least six weeks after the dose is administered to check for CBC (Complete blood count).
- Carmuther 100mg Injection should be administered carefully without touching the skin as it can cause serious hyperpigmentation. Hence where gloves during administration.
