About Pamorelin LA 11.25mg Injection
Pamorelin LA 11.25mg Injection belongs to the class of ‘anti-neoplastic agents’, primarily used to treat prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Prostate cancer is the prostate gland’s cancer (a small gland under the bladder secretes fluid that nourishes and protects sperm) found only in men. Endometriosis is a disorder in which tissue lining the uterus grows outside the uterine cavity. Precocious puberty occurs when a child’s body changes into that of an adult or experiences puberty too soon.
Pamorelin LA 11.25mg Injection contains Triptorelin that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. Triptorelin is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. The lowering of testosterone hormone levels in men helps slows down the growth of cancer cells in prostate cancer.
Use Pamorelin LA 11.25mg Injection as prescribed by your doctor. Your doctor will decide the dosage depending on your medical condition. The common side effects of Pamorelin LA 11.25mg Injection include hot flashes, decreased sexual interest, shrinking of the testicles, breast tenderness or swelling, dizziness, headache, flu symptoms, nausea, vomiting, diarrhoea, upset stomach and swelling in legs. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
Do not take or stop this medicine, if the doctor did not advise you to do so. Before starting Pamorelin LA 11.25mg Injection, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Pamorelin LA 11.25mg Injection is not indicated for use in pregnant and breastfeeding women. Pamorelin LA 11.25mg Injection may make you feel dizzy, hence drive when you are alert only. Pamorelin LA 11.25mg Injection is not recommended for children below two years of age.
Uses Of Pamorelin LA 11.25mg Injection
- Prostate cancer, endometriosis and precocious puberty.
Medicinal Benefits
Pamorelin LA 11.25mg Injection contains Triptorelin, a gonadotropin-releasing hormone (GnRH) agonist. It treats prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Pamorelin LA 11.25mg Injection is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. Being an anti-neoplastic or anticancer agent, Pamorelin LA 11.25mg Injection works by lowering testosterone levels in men that help stop the growth of cancer cells in prostate cancer. Pamorelin LA 11.25mg Injection reduces oestrogen (a hormone required for the development and regulation of the female reproductive system and secondary sexual characteristics) levels in women, thus helps in shrinking of endometriosis. Pamorelin LA 11.25mg Injection also has the role of a contraceptive drug.
Directions For Use
Storage
- Store in a cool and dry place away from sunlight
Side Effects Of Pamorelin LA 11.25mg Injection
- Hot flashes
- Decreased sexual interest
- Shrinking of the testicles
- Breast tenderness or swelling
- Dizziness
- Headache
- Flu
- Nausea
- Vomiting
- Diarrhoea
- Upset stomach
- Swelling in legs
Precautions And Warning
Inform your doctor if you have any allergic reactions to Pamorelin LA 11.25mg Injection or other medications. Before starting Pamorelin LA 11.25mg Injection, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Pamorelin LA 11.25mg Injection may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) and may affect heart rhythm, hence heart patients should be cautious while taking Pamorelin LA 11.25mg Injection. Pamorelin LA 11.25mg Injection can affect the unborn baby when used in pregnancy. Hence, Pamorelin LA 11.25mg Injection is not indicated for use in pregnancy and breastfeeding women. If you are using Pamorelin LA 11.25mg Injection, make sure to use reliable forms of contraception to prevent pregnancy during the course. Pamorelin LA 11.25mg Injection may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Pamorelin LA 11.25mg Injection can make you feel dizzy and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Pamorelin LA 11.25mg Injection is not recommended for children younger than two years of age.
Interactions
Drug Interaction: Pamorelin LA 11.25mg Injection may interact with heart rhythm problems treating drugs (quinidine, procainamide, amiodarone, sotalol), antibiotics (moxifloxacin), opioid pain killers (methadone) and antipsychotics.
Food Interaction: No interactions found/established.
Disease Interaction: Pamorelin LA 11.25mg Injection should be used with caution in cases of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels.
Drug Interactions
- Quinidine
- Procainamide
- Amiodarone
- Sotalol
- Moxifloxacin
- Methadone
Safety Advice
Alcohol
It is advised to avoid alcohol consumption to minimize the unwanted effects of Pamorelin LA 11.25mg Injection. Please consult your doctor for more information.
Pregnancy
Pamorelin LA 11.25mg Injection is a pregnancy category X drug. It is unsafe to use Pamorelin LA 11.25mg Injection in pregnancy and can have harmful effects on the unborn baby. Use reliable forms of contraception to prevent pregnancy while using Pamorelin LA 11.25mg Injection.
Breast Feeding
Pamorelin LA 11.25mg Injection is unsafe to use during breastfeeding. Consult your doctor for further information.
Driving
Pamorelin LA 11.25mg Injection causes dizziness and affects your ability to drive. Do not drive or operate machinery if you experience any unmanageable side effects with Pamorelin LA 11.25mg Injection.
Liver
Please let your doctor know if you have any history of liver diseases or hepatic impairment before starting Pamorelin LA 11.25mg Injection.
Kidney
Please let your doctor know if you have any history of kidney diseases before starting Pamorelin LA 11.25mg Injection.
Children
Pamorelin LA 11.25mg Injection is not recommended in children younger than two years of age.
Diet & Lifestyle Advise
- Take the medication as directed by the doctor and at regular intervals.
- Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
- Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
- Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products.
- Exercise regularly to lose weight as obesity is also considered as a risk factor for prostate cancer.
- Eat at regular intervals.
- Keep your weight under control with BMI 19.5-24.9.
- Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.
Special Advise
- Your doctor may advise liver function tests to monitor your liver health since Pamorelin LA 11.25mg Injection may cause increased liver enzymes (alanine aminotransferase, serum aspartate and serum transaminases).
- Pamorelin LA 11.25mg Injection may cause increased serum glucose levels (hyperglycaemia), hence inform your doctor if you have diabetes before starting Pamorelin LA 11.25mg Injection.
- Your doctor may advise blood tests and regular examinations of the prostate.
- It is advised to get an electrocardiogram (ECG) done timely to monitor your heart health.
